Protein Alignment CG6462 and PRSS3

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001184026.3
• Gene: PRSS3 / 5646
• HGNCID: 9486
• Length: 261
• Species: Homo sapiens
• Alignment Length: 256
• Identity: 76/256 - (29%)
• Similarity: 111/256 - (43%)
• Gaps: 49/256 - (19%)

  Fly    76 RIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGATVFAD 140
            :|.||........||||.|   .||:..  ||||||:.|:|::||||....|..::
Human    37 KIVGGYTCEENSLPYQVSL---NSGSHF--CGGSLISEQWVVSAAHCYKTRIQVRL--------- 87

  Fly   141 VEDSVEELQ-----VTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIEL-----AGEFM 195
            .|.:::.|:     :.....|.:|.|......:|:.||:|......:.:|..|.|     |
Human    88 GEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARVSTISLPTTPPA---- 148

  Fly   196 HQNFLVGKVVTLSGWG----YLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHLCTDG 256
                 .|....:||||    :..|..|:    |:.|||.|:.|..|...: ||.::.........
Human   149 -----AGTECLISGWGNTLSFGADYPDE----LKCLDAPVLTQAECKASY-PGKITNSMFCVGFL 203

  Fly   257 SNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGCE-VGGPTVYTRITAYLPWIRQQTA 316
            ..|:.:|..|||||||.:    ..|.||.|:|  .||. ...|.|||::..|:.||:...|
Human   204 EGGKDSCQRDSGGPVVCN----GQLQGVVSWG--HGCAWKNRPGVYTKVYNYVDWIKDTIA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	75/251 (30%)
PRSS3	NP_001184026.3	Tryp_SPc	38..256	CDD:238113	75/251 (30%)