Protein Alignment CG6462 and PRSS2

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 78/257 - (30%)
• Similarity: 113/257 - (43%)
• Gaps: 37/257 - (14%)

  Fly    76 RIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGATVFAD 140
            :|.||.:......||||.|   .||...  ||||||:.|:|::|.||...||.:|:......:..
Human    23 KIVGGYICEENSVPYQVSL---NSGYHF--CGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHR 82

  Fly   141 V-----EDSVEELQ-----VTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIEL----- 190
            :     |.::|.|:     :.....|.:|.|......:|:.||:|......:.:|..|.|
Human    83 IQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTAPP 147

  Fly   191 AGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHLCTD 255
            |         .|....:||||....|.......||.|||.|:.|..|...: ||.::........
Human   148 A---------AGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEASY-PGKITNNMFCVGF 202

  Fly   256 GSNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWIRQQTA 316
            ...|:.:|.||||||||.:    ..|.|:.|:|  .|| :...|.|||::..|:.||:...|
Human   203 LEGGKDSCQGDSGGPVVSN----GELQGIVSWG--YGCAQKNRPGVYTKVYNYVDWIKDTIA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	77/252 (31%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	77/252 (31%)