Protein Alignment CG6462 and PRSS1

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_002760.1
• Gene: PRSS1 / 5644
• HGNCID: 9475
• Length: 247
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 77/252 - (30%)
• Similarity: 110/252 - (43%)
• Gaps: 41/252 - (16%)

  Fly    76 RIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGATVFAD 140
            :|.||........||||.|   .||...  ||||||..|:|::|.||....|..::
Human    23 KIVGGYNCEENSVPYQVSL---NSGYHF--CGGSLINEQWVVSAGHCYKSRIQVRL--------- 73

  Fly   141 VEDSVEELQ-----VTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIEL-----AGEFM 195
            .|.::|.|:     :.....|.:|.|......:|:.||:|..:...:.:|..|.|     |
Human    74 GEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPA---- 134

  Fly   196 HQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHLCTDGSNGR 260
                 .|....:||||....|.......||.|||.|:.|.:|...: ||.::...........|:
Human   135 -----TGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASY-PGKITSNMFCVGFLEGGK 193

  Fly   261 GACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWIRQQTA 316
            .:|.||||||||.:    ..|.||.|:|  :|| :...|.|||::..|:.||:...|
Human   194 DSCQGDSGGPVVCN----GQLQGVVSWG--DGCAQKNKPGVYTKVYNYVKWIKNTIA 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	76/247 (31%)
PRSS1	NP_002760.1	Tryp_SPc	23..239	CDD:214473	74/245 (30%)