Protein Alignment CG6462 and KLK15

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_059979.2
• Gene: KLK15 / 55554
• HGNCID: 20453
• Length: 256
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 76/249 - (30%)
• Similarity: 115/249 - (46%)
• Gaps: 32/249 - (12%)

  Fly    77 IAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGATVFADV 141
            :.|.|.|.... |:||.|..:    ....||.|||:..:||:||||.:..:..::  |......
Human    23 LEGDECAPHSQ-PWQVALYER----GRFNCGASLISPHWVLSAAHCQSRFMRVRL--GEHNLRK- 79

  Fly   142 EDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQNFLVGKVVT 206
            .|..|:|:.|.| .|.:|.|......:|:.|:||.:..|.:.||:|..|.....|.    |:...
Human    80 RDGPEQLRTTSR-VIPHPRYEARSHRNDIMLLRLVQPARLNPQVRPAVLPTRCPHP----GEACV 139

  Fly   207 LSGWGYL-----GDSTDKRTRL-----LQYLDAEVIDQERCICYFLPGLVSQRRHLCTDGSNGRG 261
            :||||.:     |.:...|:::     |...:..:|....|...: ||.::... :|. |:.|||
Human   140 VSGWGLVSHNEPGTAGSPRSQVSLPDTLHCANISIISDTSCDKSY-PGRLTNTM-VCA-GAEGRG 201

  Fly   262 A--CNGDSGGPVVYHWRNVSYLIGVTSFGSAEGCEVGGPTVYTRITAYLPWIRQ 313
            |  |.||||||:|..    ..|.|:.|:|.........|.|||::..||.|||:
Human   202 AESCEGDSGGPLVCG----GILQGIVSWGDVPCDNTTKPGVYTKVCHYLEWIRE 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	76/249 (31%)
KLK15	NP_059979.2	Tryp_SPc	25..249	CDD:214473	73/243 (30%)