Protein Alignment CG6462 and Cfd

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001071110.1
• Gene: Cfd / 54249
• RGDID: 2498
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 245
• Identity: 70/245 - (28%)
• Similarity: 114/245 - (46%)
• Gaps: 19/245 - (7%)

  Fly    71 AAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCL---TDAIAAKIY 132
            |..|.||.||:.|.....||...  :|::|..:  |||:|:..|:||:||||:   |.....::.
  Rat    20 AQPRGRILGGQEAMAHARPYMAS--VQVNGTHV--CGGTLVDEQWVLSAAHCMDGVTKDEVVQVL 80

  Fly   133 TGATVFADVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQ 197
            .||...:..|.......|  :..:::|.........||.|.:|.........|:|:.|..|  .:
  Rat    81 LGAHSLSSPEPYKHLYDV--QSVVLHPGSRPDSVEDDLMLFKLSHNASLGPHVRPLPLQRE--DR 141

  Fly   198 NFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERC-ICYFLPGLVSQRRHLCTDGSNGRG 261
            ....|.:..::|||.: ....:|..:||.|...::|:..| :..:..|.:: :..:|.: ||.|.
  Rat   142 EVKPGTLCDVAGWGVV-THAGRRPDVLQQLTVSIMDRNTCNLRTYHDGAIT-KNMMCAE-SNRRD 203

  Fly   262 ACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGCEVGGPTVYTRITAYLPWI 311
            .|.||||||:|..    ..:..|.::||........|.|:||:..|:|||
  Rat   204 TCRGDSGGPLVCG----DAVEAVVTWGSRVCGNRRKPGVFTRVATYVPWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	67/239 (28%)
Cfd	NP_001071110.1	Tryp_SPc	26..252	CDD:238113	67/239 (28%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		1/3 (33%)