DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG6462 and prss60.2

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001099071.1	Gene:	prss60.2 / 541408	ZFINID:	ZDB-GENE-050320-109	Length:	328	Species:	Danio rerio

Alignment Length:	245	Identity:	76/245 - (31%)
Similarity:	114/245 - (46%)	Gaps:	12/245 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 AAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAK--IYT 133
            |.:.:||.||..|..|.:|:||.|.....|...  ||||||:.::||||||||.....:.  :|.
Zfish    28 APLNSRIVGGVNAPEGSWPWQVSLQSPRYGGHF--CGGSLISSEWVLTAAHCLPGVSESSLVVYL 90

  Fly   134 GATVFADVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQN 198
            |......|  :..|........|::..|......:|:||:||...|..::.::|:.||.:  :..
Zfish    91 GRRTQQGV--NTHETSRNVAKIIVHSSYNSNTNDNDIALLRLSSAVTFNDYIRPVCLAAQ--NSV 151

  Fly   199 FLVGKVVTLSGWGYLGDSTD-KRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHLCTDGSNGRGA 262
            :..|....::|||.:....: ....:||.....|:..:||......|.|:...........|:..
Zfish   152 YSAGTSSWITGWGDVQAGVNLPAPGILQETMIPVVANDRCNAQLGSGTVTNNMICAGLAKGGKDT 216

  Fly   263 CNGDSGGPVVYHWRNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWI 311
            |.||||||:|.....|....|:||:|  .|| :...|.||||::.|..||
Zfish   217 CQGDSGGPMVTRLCTVWIQAGITSWG--YGCADPNSPGVYTRVSQYQSWI 264

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	73/238 (31%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	74/239 (31%)
prss60.2	NP_001099071.1	Tryp_SPc	33..264	CDD:214473	73/238 (31%)
		Tryp_SPc	34..267	CDD:238113	74/239 (31%)
		Somatomedin_B	296..326	CDD:295334
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587860
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940