DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and C1s1

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001091086.1	Gene:	C1s1 / 50908	MGIID:	1355312	Length:	694	Species:	Mus musculus

Alignment Length:	304	Identity:	86/304 - (28%)
Similarity:	130/304 - (42%)	Gaps:	76/304 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 RW---QLGYENFRLRC--------EKFEMEGNQTAAVRTRIAGGELATRGMFPYQVGLVIQLSGA 101
            ||   |||.|  ..||        |.|:        |..||.||:.|....||:||..
Mouse   414 RWVNDQLGIE--LPRCIPACGVPTEPFQ--------VHQRIFGGQPAKIENFPWQVFF------- 461

  Fly   102 DLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGA-TVFADVEDSVEELQVTHRDFIIYPDY---- 161
            :..:..|:||...:||||||.|.......:|.|. :|...:.::.:.| .:.|.| |:|.:
Mouse   462 NHPRASGALINEYWVLTAAHVLEKISDPLMYVGTMSVRTTLLENAQRL-YSKRVF-IHPSWKKED 524

  Fly   162 -----LGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQNFLVGKVVTLSGWGYLGDSTDKRT 221
                 ..|.  :|:||::|...|:...:|.||.|.|.....|...|.:..:||||    ||:|:.
Mouse   525 DPNTRTNFD--NDIALVQLKDPVKMGPKVSPICLPGTSSEYNVSPGDMGLISGWG----STEKKV 583

  Fly   222 RLLQYLDAEV----------IDQERCICYFLPGLVSQRRHLCTD-----GSNGRGACNGDSGGPV 271
            .::....|:|          :.:|.       ..|....::.||     |..|..:|:|||||..
Mouse   584 FVINLRGAKVPVTSLETCKQVKEEN-------PTVRPEDYVFTDNMICAGEKGVDSCHGDSGGAF 641

  Fly   272 VYHWRNVS----YLIGVTSFGSAEGCEVGGPTVYTRITAYLPWI 311
            .:...||:    |:.|:.|:|  :.|...|  |||::..|:.||
Mouse   642 AFQVPNVTVPKFYVAGLVSWG--KRCGTYG--VYTKVKNYVDWI 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	73/263 (28%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	74/264 (28%)
C1s1	NP_001091086.1	CUB	24..135	CDD:238001
		FXa_inhibition	149..177	CDD:373209
		CUB	181..293	CDD:366096
		CCP	307..361	CDD:153056
		CCP	365..428	CDD:153056	7/15 (47%)
		Tryp_SPc	443..681	CDD:214473	73/263 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000