Protein Alignment CG6462 and KLK12

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 89/269 - (33%)
• Similarity: 122/269 - (45%)
• Gaps: 50/269 - (18%)

  Fly    51 LGYENFRLRCEKFEMEGNQTAAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQF 115
            :|...|.|.|    :.|...||. .:|..|....|...|:||||   ..|..| :|||.||..::
Human     1 MGLSIFLLLC----VLGLSQAAT-PKIFNGTECGRNSQPWQVGL---FEGTSL-RCGGVLIDHRW 56

  Fly   116 VLTAAHCLTDAIAAKIYTGATVFADV-EDSVEEL----QVTHRDF-IIYPDYLG--FGGYSDLAL 172
            |||||||          :|:..:..: |.|:.:|    |:.|..| :.:|.|||  .....||.|
Human    57 VLTAAHC----------SGSRYWVRLGEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRL 111

  Fly   173 IRLPRKVRTSEQVQPIEL------AGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEV 231
            :||...||.:..|||:.|      ||...|          :||||......:....|||.|:..:
Human   112 LRLRLPVRVTSSVQPLPLPNDCATAGTECH----------VSGWGITNHPRNPFPDLLQCLNLSI 166

  Fly   232 IDQERCICYFLPGLVSQRRHLCTDGSNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGC-EV 295
            :....|...: ||.::... :|..|..|:.||.||||||:|..    ..|.|:.|:||...| :.
Human   167 VSHATCHGVY-PGRITSNM-VCAGGVPGQDACQGDSGGPLVCG----GVLQGLVSWGSVGPCGQD 225

  Fly   296 GGPTVYTRI 304
            |.|.|||.|
Human   226 GIPGVYTYI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	82/243 (34%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	82/243 (34%)