Protein Alignment CG6462 and KLK14

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 73/252 - (28%)
• Similarity: 114/252 - (45%)
• Gaps: 29/252 - (11%)

  Fly    69 QTAAVRTRIAGGELATRGMFPYQVGLVIQLSG-ADLVKCGGSLITLQFVLTAAHCLTDAIAAKIY 132
            |:.....:|.||...||...|:|..|   |:| .....|||:|::.|:|:|||||....:  ::.
Human    17 QSQEDENKIIGGHTCTRSSQPWQAAL---LAGPRRRFLCGGALLSGQWVITAAHCGRPIL--QVA 76

  Fly   133 TGATVFADVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQ 197
            .|.......|.:.:.|:|..:  :.:|:|......:||.|::|.:..|....|:|||:.......
Human    77 LGKHNLRRWEATQQVLRVVRQ--VTHPNYNSRTHDNDLMLLQLQQPARIGRAVRPIEVTQACASP 139

  Fly   198 NFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYF----LPGLVSQRRHLCTD-GS 257
                |....:||||.:.....:....||.::..:...|.|...:    .||:|      |.. ..
Human   140 ----GTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPRTITPGMV------CAGVPQ 194

  Fly   258 NGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGCEVGG-PTVYTRITAYLPWIRQ 313
            .|:.:|.||||||:|..    ..|.|:.|:| .|.|.:.| |.|||.:..|..||.:
Human   195 GGKDSCQGDSGGPLVCR----GQLQGLVSWG-MERCALPGYPGVYTNLCKYRSWIEE 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	72/244 (30%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	72/244 (30%)