DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and CG9737

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_651783.1	Gene:	CG9737 / 43600	FlyBaseID:	FBgn0039758	Length:	424	Species:	Drosophila melanogaster

Alignment Length:	275	Identity:	81/275 - (29%)
Similarity:	119/275 - (43%)	Gaps:	50/275 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 VRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHC-----LTDAIAAK-I 131
            |..||.|||:|....||:   |.:.:..::...|.|:||..:.:||||||     :.|....| :
  Fly   146 VTNRIYGGEIAELDEFPW---LALLVYNSNDYGCSGALIDDRHILTAAHCVQGEGVRDRQGLKHV 207

  Fly   132 YTGATVFADVEDSVEE----------LQVTHRDFIIYPDYLGFGG--YSDLALIRLPRKVRTSEQ 184
            ..|........|.:||          |.:.:....::|:|..|..  |:|:|:|||...|..:..
  Fly   208 RLGEFNVKTEPDCIEEPNYLSCADAALDIAYEKIHVHPEYKEFSNYKYNDIAIIRLKHPVSFTHF 272

  Fly   185 VQPIELAGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLL-QY-----------LDAEVIDQERC 237
            |.||.|..:........|::.::||||        ||.|. :|           |....:..|.|
  Fly   273 VMPICLPNKSEPLTLAEGQMFSVSGWG--------RTDLFNKYFINIHSPIKLKLRIPYVSNENC 329

  Fly   238 ICYFLPGLVSQ--RRHLCTDGSNGRGACNGDSGGPVVY----HWRNVSYLIGVTSFGSAEGCEVG 296
             ...|.|...:  .:.:|..|...:..|.||||||::|    |.|.|:|  ||.|:|..:....|
  Fly   330 -TKILEGFGVRLGPKQICAGGEFAKDTCAGDSGGPLMYFDRQHSRWVAY--GVVSYGFTQCGMAG 391

  Fly   297 GPTVYTRITAYLPWI 311
            .|.|||.:..|..||
  Fly   392 KPAVYTNVAEYTDWI 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	78/270 (29%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	79/271 (29%)
CG9737	NP_651783.1	CLIP	28..89	CDD:288855
		Tryp_SPc	149..406	CDD:214473	78/270 (29%)
		Tryp_SPc	150..409	CDD:238113	79/271 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457520
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
	3	2.840