Protein Alignment CG6462 and KLK2

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 72/265 - (27%)
• Similarity: 115/265 - (43%)
• Gaps: 48/265 - (18%)

  Fly    73 VRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGATV 137
            :::||.||....:...|:||.:.    ......|||.|:..|:||||||||..  .::::.|...
Human    21 IQSRIVGGWECEKHSQPWQVAVY----SHGWAHCGGVLVHPQWVLTAAHCLKK--NSQVWLGRHN 79

  Fly   138 FADVEDSVEELQVTH------------RDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIEL 190
            ..:.||:.:.:.|:|            :...:.||.   ....||.|:||....:.::.|:.:.|
Human    80 LFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDE---DSSHDLMLLRLSEPAKITDVVKVLGL 141

  Fly   191 AGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERC-------ICYFLPGLVSQ 248
            .    .|...:|.....||||.:......|.|.||.:...::..:.|       :..|:
Human   142 P----TQEPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFM------ 196

  Fly   249 RRHLCTD-GSNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGCEV-GGPTVYTRITAYLPWI 311
               ||.. .:.|:..|.||||||:|.:    ..|.|:||:| .|.|.: ..|.|||::..|..||
Human   197 ---LCAGLWTGGKDTCGGDSGGPLVCN----GVLQGITSWG-PEPCALPEKPAVYTKVVHYRKWI 253

  Fly   312 RQQTA 316
            :...|
Human   254 KDTIA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	70/257 (27%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	70/257 (27%)