Protein Alignment CG6462 and KLK3

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001639.1
• Gene: KLK3 / 354
• HGNCID: 6364
• Length: 261
• Species: Homo sapiens
• Alignment Length: 269
• Identity: 79/269 - (29%)
• Similarity: 119/269 - (44%)
• Gaps: 51/269 - (18%)

  Fly    73 VRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGATV 137
            :.:||.||....:...|:|| ||.....|   .|||.|:..|:|||||||:.:  .:.|..|...
Human    21 ILSRIVGGWECEKHSQPWQV-LVASRGRA---VCGGVLVHPQWVLTAAHCIRN--KSVILLGRHS 79

  Fly   138 FADVEDSVEELQVTHRDFIIYPDYL-------------GFGGYSDLALIRLPRKVRTSEQVQPIE 189
            ....||:.:..||:|.    :|..|             |.....||.|:||......::.|:.::
Human    80 LFHPEDTGQVFQVSHS----FPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMD 140

  Fly   190 LAGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERC-------ICYFLPGLVS 247
            |.    .|...:|.....||||.:........:.||.:|..||..:.|       :..|:
Human   141 LP----TQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFM----- 196

  Fly   248 QRRHLCTD-GSNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGCEV-GGPTVYTRITAYLPW 310
                ||.. .:.|:..|:||||||:|.:    ..|.|:||:|| |.|.: ..|::||::..|..|
Human   197 ----LCAGRWTGGKSTCSGDSGGPLVCN----GVLQGITSWGS-EPCALPERPSLYTKVVHYRKW 252

  Fly   311 IRQQTAMTN 319
            |: .|.:.|
Human   253 IK-DTIVAN 260

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	76/258 (29%)
KLK3	NP_001639.1	Tryp_SPc	25..256	CDD:238113	76/259 (29%)