Protein Alignment CG6462 and TMPRSS7

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_001382436.1
• Gene: TMPRSS7 / 344805
• HGNCID: 30846
• Length: 843
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 76/265 - (28%)
• Similarity: 131/265 - (49%)
• Gaps: 43/265 - (16%)

  Fly    68 NQTAAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHC-----LTDAI 127
            :::::...||.||.....|.:|:||.|  ...|:  ..||.|:|:.:::|:||||     |:|..
Human   597 SRSSSALHRIIGGTDTLEGGWPWQVSL--HFVGS--AYCGASVISREWLLSAAHCFHGNRLSDPT 657

  Fly   128 AAKIYTGATVFADVEDSVEELQVTHRDFIIYPDYLGFGGYS-DLALIRL----PRKVRTSEQVQP 187
            ....:.|..    |:.:.:.:....|  |:..:|.....:. |:||::|    |..::  :.:||
Human   658 PWTAHLGMY----VQGNAKFVSPVRR--IVVHEYYNSQTFDYDIALLQLSIAWPETLK--QLIQP 714

  Fly   188 IEL--AGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRR 250
            |.:  .|    |....|:...::|||...::.:|.:.:||..:.|:|||..|:..:  |:::.|.
Human   715 ICIPPTG----QRVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTY--GIITSRM 773

  Fly   251 HLCTDGSNG-RGACNGDSGGPVVYH------WRNVSYLIGVTSFGSAEGCEVGGPTVYTRITAYL 308
             ||....:| |.||.||||||:...      |    .|.|:.|:|...| ....|.||||::.::
Human   774 -LCAGIMSGKRDACKGDSGGPLSCRRKSDGKW----ILTGIVSWGHGSG-RPNFPGVYTRVSNFV 832

  Fly   309 PWIRQ 313
            |||.:
Human   833 PWIHK 837

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	75/256 (29%)
TMPRSS7	NP_001382436.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..67
		SEA	108..207	CDD:460188
		CUB	247..359	CDD:238001
		LDLa	484..518	CDD:238060
		LDLa	559..594	CDD:238060
		Tryp_SPc	605..835	CDD:214473	74/253 (29%)