Protein Alignment CG6462 and TMPRSS11A

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_872412.3
• Gene: TMPRSS11A / 339967
• HGNCID: 27954
• Length: 421
• Species: Homo sapiens
• Alignment Length: 261
• Identity: 72/261 - (27%)
• Similarity: 120/261 - (45%)
• Gaps: 47/261 - (18%)

  Fly    76 RIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCL---------TDAIAAKI 131
            |||.|.:|.:..:|:|..|...    ::.:||.:||:..:::|||||.         |.:...||
Human   189 RIASGVIAPKAAWPWQASLQYD----NIHQCGATLISNTWLVTAAHCFQKYKNPHQWTVSFGTKI 249

  Fly   132 YTGATVFADVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMH 196
                        :...::...|.|||:..|.......|:|::::..:|..|:.::.|.|..  ..
Human   250 ------------NPPLMKRNVRRFIIHEKYRSAAREYDIAVVQVSSRVTFSDDIRQICLPE--AS 300

  Fly   197 QNFLVGKVVTLSGWG---YLGDS-TDKRTRLLQYLDAEVIDQERCICY---FLPGLVSQRRHLCT 254
            .:|.....|.::|:|   |.|:| .|.|...::.:..:|..|.:  .|   ..||:      .|.
Human   301 ASFQPNLTVHITGFGALYYGGESQNDLREARVKIISDDVCKQPQ--VYGNDIKPGM------FCA 357

  Fly   255 DGSNG-RGACNGDSGGPVVYH-WRNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWIRQQTA 316
            ....| ..||.||||||:|.. .::..||||:.|:|  :.| :...|.|||::|.|..||..:|.
Human   358 GYMEGIYDACRGDSGGPLVTRDLKDTWYLIGIVSWG--DNCGQKDKPGVYTQVTYYRNWIASKTG 420

  Fly   317 M 317
            :
Human   421 I 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	70/255 (27%)
TMPRSS11A	NP_872412.3	SEA	49..149	CDD:460188
		Tryp_SPc	190..418	CDD:238113	70/255 (27%)