Protein Alignment CG6462 and PRSS38

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_898885.1
• Gene: PRSS38 / 339501
• HGNCID: 29625
• Length: 326
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 84/282 - (29%)
• Similarity: 130/282 - (46%)
• Gaps: 60/282 - (21%)

  Fly    60 CEKFEMEGNQTAAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLT 124
            |.:..|||        :|.||..|....:|:||    .:..|.|..||||::...:||:||||..
Human    51 CGRPSMEG--------KILGGVPAPERKWPWQV----SVHYAGLHVCGGSILNEYWVLSAAHCFH 103

  Fly   125 DAIAAKIYTGATVFADVEDSVEELQV--THRDF------IIYPDYLGF---GGYSDLALIRLPRK 178
            .....|||       |:...:..|:|  .|..:      |::|.|..:   ||  |:||::|..:
Human   104 RDKNIKIY-------DMYVGLVNLRVAGNHTQWYEVNRVILHPTYEMYHPIGG--DVALVQLKTR 159

  Fly   179 VRTSEQVQPIELAGEFMHQNFLVGKVVTLSGWGYL---GDSTDKRTRLLQYLDAEVIDQERC--- 237
            :..||.|.|:.||...::   |.......:|||.:   |:::|:    ||.:...:|.:..|
Human   160 IVFSESVLPVCLATPEVN---LTSANCWATGWGLVSKQGETSDE----LQEMQLPLILEPWCHLL 217

  Fly   238 ---ICYFLPGLVSQRRHLCT-DGSNGRGACNGDSGGPVVYHWRNVSYL-IGVTSFGSAEGCEVG- 296
               :.|.:|.:      ||. |..|.:..|.||||||:|..: |.|:| ||:.|:|  .||...
Human   218 YGHMSYIMPDM------LCAGDILNAKTVCEGDSGGPLVCEF-NRSWLQIGIVSWG--RGCSNPL 273

  Fly   297 GPTVYTRITAYLPWIRQQTAMT 318
            .|.||..::.:..||.....:|
Human   274 YPGVYASVSYFSKWICDNIEIT 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	79/259 (31%)
PRSS38	NP_898885.1	Tryp_SPc	60..291	CDD:238113	79/259 (31%)