DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and HABP2

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_004123.1	Gene:	HABP2 / 3026	HGNCID:	4798	Length:	560	Species:	Homo sapiens

Alignment Length:	318	Identity:	85/318 - (26%)
Similarity:	131/318 - (41%)	Gaps:	91/318 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 EETPDDDDAIMERRWQLGYENFRLRCEKFEMEGNQTAAVRTRIAGGELATRGMFPYQV----GLV 95
            ||:|.:....:.     |:::    |.|.|:...:.    .||.||..:|.|..|:|.    .|.
Human   285 EESPTEPSTKLP-----GFDS----CGKTEIAERKI----KRIYGGFKSTAGKHPWQASLQSSLP 336

  Fly    96 IQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGATVFADVEDSVEE-----------LQ 149
            :.:|......|||:||...:||||||| ||.....:   ..|..|.:...||           .:
Human   337 LTISMPQGHFCGGALIHPCWVLTAAHC-TDIKTRHL---KVVLGDQDLKKEEFHEQSFRVEKIFK 397

  Fly   150 VTH---RDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIE----LAGEFMHQ------NFLV 201
            .:|   ||.|         .::|:||::|          :|::    |..:::..      :|..
Human   398 YSHYNERDEI---------PHNDIALLKL----------KPVDGHCALESKYVKTVCLPDGSFPS 443

  Fly   202 GKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRR---HLCTDG------- 256
            |....:||||.  ..|.|.:|  |.|||:|......:|       :.|:   |:..|.
Human   444 GSECHISGWGV--TETGKGSR--QLLDAKVKLIANTLC-------NSRQLYDHMIDDSMICAGNL 497

  Fly   257 -SNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGCEVG-GPTVYTRITAYLPWIR 312
             ..|:..|.||||||:........|:.|:.|:    |.|.| .|.|||::|.:|.||:
Human   498 QKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSW----GLECGKRPGVYTQVTKFLNWIK 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	76/274 (28%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	77/276 (28%)
HABP2	NP_004123.1	EGF	77..106	CDD:306513
		KR	191..277	CDD:238056
		Tryp_SPc	314..553	CDD:238113	77/276 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000