Protein Alignment CG6462 and GZMB

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_004122.2
• Gene: GZMB / 3002
• HGNCID: 4709
• Length: 247
• Species: Homo sapiens
• Alignment Length: 250
• Identity: 73/250 - (29%)
• Similarity: 111/250 - (44%)
• Gaps: 41/250 - (16%)

  Fly    77 IAGGELATRGMFPYQVGLVI--QLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGATVFA 139
            |.||..|.....||...|:|  |.|   |.:|||.||...||||||||...:|  .:..||....
Human    21 IIGGHEAKPHSRPYMAYLMIWDQKS---LKRCGGFLIRDDFVLTAAHCWGSSI--NVTLGAHNIK 80

  Fly   140 DVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQNFLVGKV 204
            :.|.:.:.:.|...  |.:|.|......:|:.|::|.||.:.:..|||:.|...  ......|:.
Human    81 EQEPTQQFIPVKRP--IPHPAYNPKNFSNDIMLLQLERKAKRTRAVQPLRLPSN--KAQVKPGQT 141

  Fly   205 VTLSGWGY---LGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRRH-------LCT-DGSN 258
            .:::|||.   ||    |.:..||.:...|.:..:|        .|..||       ||. |...
Human   142 CSVAGWGQTAPLG----KHSHTLQEVKMTVQEDRKC--------ESDLRHYYDSTIELCVGDPEI 194

  Fly   259 GRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGCEVGGPTVYTRITAYLPWIRQ 313
            .:.:..||||||:|.:    ....|:.|:|...|..   |...|::::::.||::
Human   195 KKTSFKGDSGGPLVCN----KVAQGIVSYGRNNGMP---PRACTKVSSFVHWIKK 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	73/249 (29%)
GZMB	NP_004122.2	Tryp_SPc	21..243	CDD:238113	73/249 (29%)