Protein Alignment CG6462 and TMPRSS12

DIOPT Version :9

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 89/318 - (27%)
• Similarity: 144/318 - (45%)
• Gaps: 23/318 - (7%)

  Fly    12 LLLLSSTLVKSSEPWLDTFEHPKEET--PDDDDAIMERRWQLGYENFRLRCE-KFEMEGNQTAAV 73
            ||.::...|.||..:.|.:.......  |..:.|...::.:...:..|.|.| ....|...||.:
Human     5 LLSVALLFVGSSHLYSDHYSPSGRHRLGPSPEPAASSQQAEAVRKRLRRRREGGAHAEDCGTAPL 69

  Fly    74 R-----TRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYT 133
            :     :||.||..|..|.:|:.|.|.|:.....:..|||:|:..::|||||||..||....::|
Human    70 KDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWT 134

  Fly   134 GATVFADVEDSVEEL-QVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQ 197
            ......::....... ::..:..||:|:::.....:|:||..|.:.||.::.:|||.|..:..
Human   135 AVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVF-- 197

  Fly   198 NFLVGKV-VTLSGWGYLGDSTDKRTRLLQYLDAEV--IDQERCICYFLPGLVSQRRHLCTDGSNG 259
            ..|.|.. ..:||||...:. ...|.:||  ||||  |.:|.|......|.:......|....:|
Human   198 QILDGNTKCFISGWGRTKEE-GNATNILQ--DAEVHYISREMCNSERSYGGIIPNTSFCAGDEDG 259

  Fly   260 R-GACNGDSGGPVVYHWRNVS--YLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWIRQ 313
            . ..|.||||||::.:.....  :::|:||:|  .|| ..|.|.||...:.|..|:.:
Human   260 AFDTCRGDSGGPLMCYLPEYKRFFVMGITSYG--HGCGRRGFPGVYIGPSFYQKWLTE 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	74/242 (31%)
		Tryp_SPc	77..314	CDD:238113	74/245 (30%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..63		5/38 (13%)
		Tryp_SPc	78..316	CDD:238113	74/245 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24253
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100