DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and F7

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_690059.1	Gene:	F7 / 260320	RGDID:	628678	Length:	446	Species:	Rattus norvegicus

Alignment Length:	302	Identity:	84/302 - (27%)
Similarity:	136/302 - (45%)	Gaps:	66/302 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PKEETPDDDDAIMERRWQLGYENFRLRCEKFEMEGNQTAAVRTRIAGGELATRGMFPYQVGLVIQ 97
            ||.|.|.....::|:|      ||              :..:.||.||.:..:|..|:|.  |::
  Rat   170 PKVEYPCGRIPVVEKR------NF--------------SRPQGRIVGGYVCPKGECPWQA--VLK 212

  Fly    98 LSGADLVKCGGSLITLQFVLTAAHCLT---DAIAAKIYTGATVFADVEDSVEELQVTHRDFIIYP 159
            .:.|.|  ||..|:..::::|||||..   ..:...:..|...|:: ::..|::::..:  :|.|
  Rat   213 FNEALL--CGAVLLDTRWIVTAAHCFDKFGKLVNITVVLGEHDFSE-KEGTEQVRLVEQ--VIMP 272

  Fly   160 DYLGFGGYS-DLALIRLPRKVRTSEQVQPIELAGEFMHQNFLVG-KVVTLSGWGYLGDSTDKRTR 222
            :....|... |:||:||.|.|..::.|.|:.|......:|.|.. :...:||||.|   .|:...
  Rat   273 NKYTRGRTDHDIALVRLHRPVTFTDYVVPLCLPERAFSENTLASIRFSRVSGWGQL---LDRGAT 334

  Fly   223 LLQYLDAEVIDQERCICYFLPGLVSQ-----RRH-----------LCTDGSNG-RGACNGDSGGP 270
            .|:.:..||           |.|::|     .:|           .|....:| :.||.||||||
  Rat   335 ALELMVIEV-----------PRLMTQDCLEHAKHSANTPRITENMFCAGYMDGTKDACKGDSGGP 388

  Fly   271 VVYHWRNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWI 311
            ...|:....||.||.|:|  ||| .:|...||||::.|:.|:
  Rat   389 HATHYHGTWYLTGVVSWG--EGCAAIGHIGVYTRVSQYIDWL 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	75/257 (29%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	75/258 (29%)
F7	NP_690059.1	GLA	25..85	CDD:214503
		EGF_CA	87..123	CDD:238011
		Tryp_SPc	194..430	CDD:238113	75/258 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000