DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and mst1

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_694512.1	Gene:	mst1 / 259260	ZFINID:	ZDB-GENE-020806-3	Length:	709	Species:	Danio rerio

Alignment Length:	314	Identity:	85/314 - (27%)
Similarity:	131/314 - (41%)	Gaps:	55/314 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 PWLDTFEHPKEETPDDDDAIMERRWQLGYENFRLRCEKFEMEGNQTA------AVRTRIAGGELA 83
            ||..|.: ||.|.  |..||.    |...|...:.....|:|.|:..      ..|.||.||
Zfish   431 PWCYTSD-PKTEF--DYCAIK----QCAGEKVPIIGPTTEVEFNECGKREDRLRSRLRIVGG--- 485

  Fly    84 TRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDA-IAAKIYTG--ATVFADVEDSV 145
            |.|..|:.|.| ....|...  |||||::.::|::...|.:.. :....||.  .|:|.|.::..
Zfish   486 TPGNSPWTVSL-RDRKGNHF--CGGSLVSSEWVISTKQCFSSCYVDLTGYTAMMGTLFRDPKEGE 547

  Fly   146 EELQ-VTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQNFLV--GKVVTL 207
            .:|| ::....:..|      ..|.|.:::|....:.:|:|..|.|..|    .::|  |.:..:
Zfish   548 PDLQRISLTKIVCGP------SESHLVMLQLETPAQFNERVSQICLPPE----RYIVPDGTICEI 602

  Fly   208 SGWGYL---GDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHLCTDG-SNGRGACNGDSG 268
            :|||..   ||.|     :|......|:..:.|..|| .|.| :...:||.. ..|.|||..|.|
Zfish   603 AGWGETKGKGDET-----VLNVAQMPVLSNKDCNQYF-KGRV-RENEMCTMAFQAGVGACERDYG 660

  Fly   269 GPVVYH----WRNVSYLIGVTSFGSAEGCEVGGPTVYTRITAYLPWIRQQTAMT 318
            ||:...    |.....:|.:...|.|     |.|.::.|::.|:.||::...||
Zfish   661 GPLACQNSDCWVLEGVIIPMRRCGHA-----GQPNIFIRVSVYVDWIKKVMEMT 709

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	66/248 (27%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	67/250 (27%)
mst1	NP_694512.1	PAN_AP_HGF	24..105	CDD:238532
		KR	109..187	CDD:238056
		KR	192..271	CDD:214527
		KR	284..365	CDD:214527
		KR	370..451	CDD:238056	10/26 (38%)
		Tryp_SPc	481..702	CDD:214473	66/248 (27%)
		Tryp_SPc	482..705	CDD:238113	67/250 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910