DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and Plat

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_037283.2	Gene:	Plat / 25692	RGDID:	3342	Length:	559	Species:	Rattus norvegicus

Alignment Length:	366	Identity:	89/366 - (24%)
Similarity:	137/366 - (37%)	Gaps:	89/366 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YQATSAFFLLLLSSTLVKSSEPW-------------------LDTFEHPKEETPDDDDAIMERRW 49
            |:.|.:|      :|...|..||                   |....|.....||.|    .:.|
  Rat   221 YRGTHSF------TTSKASCLPWNSMILIGKTYTAWRANSQALGLGRHNYCRNPDGD----AKPW 275

  Fly    50 QLGYENFRLRCEKFEMEGNQTAAVRT------RIAGGELATRGMFPYQVGLVI--QLSGADLVKC 106
            ....::.:|..|..:|....|..:|.      ||.||........|:|..:.:  :.|..:...|
  Rat   276 CHVMKDRKLTWEYCDMSPCSTCGLRQYKQPQFRIKGGLFTDITSHPWQAAIFVKNKRSPGERFLC 340

  Fly   107 GGSLITLQFVLTAAHCLTDAIA---AKIYTGAT---VFADVEDSVE-ELQVTHRDF--IIYPDYL 162
            ||.||:..:||:||||..:...   .|:..|.|   |..:.|.:.| |..:.|::|  ..|.
  Rat   341 GGVLISSCWVLSAAHCFVERFPPHHLKVVLGRTYRVVPGEEEQTFEIEKYIVHKEFDDDTYD--- 402

  Fly   163 GFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQNFLVGKV--------------VTLSGWGYL 213
                 :|:||::|  :..:|:..|          ::..||..              ..|||:|..
  Rat   403 -----NDIALLQL--RSDSSQCAQ----------ESSSVGTACLPDPDVQLPDWTECELSGYGKH 450

  Fly   214 GDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHLCTDGSNGRG------ACNGDSGGPVV 272
            ..|:...:..|:.....:....||....|.........||...:...|      ||.||||||:|
  Rat   451 EASSPFFSDRLKEAHVRLYPSSRCTSQHLFNKTITSNMLCAGDTRTGGNQDVHDACQGDSGGPLV 515

  Fly   273 YHWRNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWIR 312
            ........|:|:.|:|.  || :...|.:||::|.||.||:
  Rat   516 CMIDKRMTLLGIISWGL--GCGQKDVPGIYTKVTNYLNWIQ 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	69/266 (26%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	70/268 (26%)
Plat	NP_037283.2	Important for binding to annexin A2. /evidence=ECO:0000250	39..49
		Kringle	124..205	CDD:395005
		KR	210..295	CDD:238056	16/83 (19%)
		Tryp_SPc	311..556	CDD:238113	69/266 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000