DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and Plau

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_037217.3	Gene:	Plau / 25619	RGDID:	3343	Length:	432	Species:	Rattus norvegicus

Alignment Length:	329	Identity:	86/329 - (26%)
Similarity:	138/329 - (41%)	Gaps:	58/329 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 EHPKEETPDDDDAIMERRW---QLGYENFRLRC-----------------EKFEMEGNQTAAVRT 75
            :|.....||:    ..|.|   |:|.:.|...|                 :.|:. |.:....|.
  Rat   118 KHNYCRNPDN----QRRPWCYVQIGLKQFVQECMVQDCSLSKKPSSTVDQQGFQC-GQKALRPRF 177

  Fly    76 RIAGGELATRGMFPYQVGLVIQLSGAD--LVKCGGSLITLQFVLTAAHCLTDAIAAK---IYTGA 135
            :|.|||.......|:...:.::..|..  ..|||||||:..:|.:|.||..:....:   :|.|.
  Rat   178 KIVGGEFTVVENQPWFAAIYLKNKGGSPPSFKCGGSLISPCWVASATHCFVNQPKKEEYVVYLGQ 242

  Fly   136 TVF-----ADVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRT--------SEQVQP 187
            :..     .:::..||:| :.|.||  ..:.|.|  ::|:||:    |:||        |..:|.
  Rat   243 SKRNSYNPGEMKFEVEQL-ILHEDF--SDETLAF--HNDIALL----KIRTSTGQCAQPSRTIQT 298

  Fly   188 IELAGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHL 252
            |.|...|....|  |....::|:|....:.....:.|:....::|..|:|......|.....:.|
  Rat   299 ICLPPRFGDAPF--GSDCEITGFGQESATDYFYPKDLKMSVVKIISHEQCKQPHYYGSEINYKML 361

  Fly   253 C-TDGSNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWIRQQT 315
            | .|......:|:||||||::.:......|.|:.|:||  || |...|.||||::.:|.||:...
  Rat   362 CAADPEWKTDSCSGDSGGPLICNIDGRPTLSGIVSWGS--GCAEKNKPGVYTRVSYFLNWIQSHI 424

  Fly   316 AMTN 319
            ...|
  Rat   425 GEEN 428

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	71/254 (28%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	73/256 (29%)
Plau	NP_037217.3	Binds urokinase plasminogen activator surface receptor	34..57
		KR	67..152	CDD:238056	9/37 (24%)
		Connecting peptide	152..178		3/26 (12%)
		Tryp_SPc	178..420	CDD:214473	71/254 (28%)
		Tryp_SPc	179..423	CDD:238113	73/256 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000