DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and Mst1

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_038936729.1	Gene:	Mst1 / 24566	RGDID:	3114	Length:	747	Species:	Rattus norvegicus

Alignment Length:	307	Identity:	81/307 - (26%)
Similarity:	130/307 - (42%)	Gaps:	45/307 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SSEPWLDT------FEHPKEETPDDDD--AIMERRWQLGYENFRLRCEKFEMEGNQTAAVRTRIA 78
            |..||..|      |::...:..|||.  :|::...|:.:|    :|.|...:.|     |.|:.
  Rat   466 SHGPWCYTLDPETLFDYCALKRCDDDQPPSILDPPVQVQFE----KCGKRVDQSN-----RLRVV 521

  Fly    79 GGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCL---TDAIAA-KIYTGATVFA 139
            ||.   .|..|:.|.| ....|...  |||||:..|:||||..|:   .|.:.. :::.| |:..
  Rat   522 GGH---PGNSPWTVSL-RNRQGQHF--CGGSLVKEQWVLTARQCIWSCHDPLTGYEVWLG-TINQ 579

  Fly   140 DVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQNFLV--G 202
            :.:.....||...    :.....|..| |.|.|::|.|.|..:..|..|.|..|    .::|  |
  Rat   580 NPQPGEANLQRVS----VAKTVCGPAG-SQLVLLKLERPVILNHHVARICLPPE----QYVVPPG 635

  Fly   203 KVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHLCTDGSNG-RGACNGD 266
            ....::|||. ...|...| :|.....:||..:.|...:...:  |...:||:|... .|||.||
  Rat   636 TNCEIAGWGE-SKGTSNST-VLHVAKMKVISSQECNVKYRRRV--QESEICTEGLLAPTGACEGD 696

  Fly   267 SGGPVVYHWRNVSYLIGVTSFGSAEGCEVGGPTVYTRITAYLPWIRQ 313
            .|||:..:..:...|.|:. ..:........|.::||::.::.||.:
  Rat   697 YGGPLACYTHDCWVLQGLI-IPNRVCARPRWPAIFTRVSVFVDWINK 742

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	64/241 (27%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	65/244 (27%)
Mst1	XP_038936729.1	PAN_1	32..111	CDD:394981
		KR	116..196	CDD:214527
		KR	199..276	CDD:214527
		KR	321..403	CDD:214527
		KR	408..490	CDD:214527	5/23 (22%)
		Tryp_SPc	520..743	CDD:238113	65/244 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000