DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and Prss8

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_620191.1	Gene:	Prss8 / 192107	RGDID:	619973	Length:	342	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	85/267 - (31%)
Similarity:	126/267 - (47%)	Gaps:	30/267 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 EGNQTAAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAK 130
            |.:..|.::.||.||..|..|.:|:||.  |..:|..:  |||||::.|:|::||||.....:.:
  Rat    34 EASCGAVIQPRITGGGSAKPGQWPWQVS--ITYNGVHV--CGGSLVSNQWVVSAAHCFPREHSKE 94

  Fly   131 IYTGATVFADVEDSVEELQVTHRDFII--------YPDYLGFGGYSDLALIRLPRKVRTSEQVQP 187
            .|       :|:....:|.....|.::        :..|...|...|:|||||...|..|..::|
  Rat    95 EY-------EVKLGAHQLDSFSNDIVVHTVAQIISHSSYREEGSQGDIALIRLSSPVTFSRYIRP 152

  Fly   188 IELAGEFMHQNFLVGKVVTLSGWGYLGDSTDKRT-RLLQYLDAEVIDQERCICYFLPGLVSQRRH 251
            |.|..  .:.:|..|...|::|||::..|...:| |.||.|:..:|.:|.|.|.:....|.:..|
  Rat   153 ICLPA--ANASFPNGLHCTVTGWGHVAPSVSLQTPRPLQQLEVPLISRETCSCLYNINAVPEEPH 215

  Fly   252 ------LCTD-GSNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGCEVGGPTVYTRITAYLP 309
                  ||.. ...|:.||.||||||:......:.||.|:.|:|.|.|.. ..|.|||..:.|..
  Rat   216 TIQQDMLCAGYVKGGKDACQGDSGGPLSCPIDGLWYLAGIVSWGDACGAP-NRPGVYTLTSTYAS 279

  Fly   310 WIRQQTA 316
            ||....|
  Rat   280 WIHHHVA 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	80/250 (32%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	81/252 (32%)
Prss8	NP_620191.1	Tryp_SPc	44..281	CDD:214473	80/250 (32%)
Prss8	NP_620191.1	Tryp_SPc	45..284	CDD:238113	81/252 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24253
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010