DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and St14

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_036010597.1	Gene:	St14 / 19143	MGIID:	1338881	Length:	875	Species:	Mus musculus

Alignment Length:	266	Identity:	84/266 - (31%)
Similarity:	129/266 - (48%)	Gaps:	30/266 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 GNQTAAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKI 131
            |.::...:.|:.||..|..|.:|:||.|.....|.   .||.|||:..::::||||..|....|.
Mouse   625 GLRSFTKQARVVGGTNADEGEWPWQVSLHALGQGH---LCGASLISPDWLVSAAHCFQDDKNFKY 686

  Fly   132 --YTGATVFADVED-------SVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQP 187
              ||..|.|..:.|       .|:||::  :..|.:|.:..|....|:||:.|.:.|..|..|:|
Mouse   687 SDYTMWTAFLGLLDQSKRSASGVQELKL--KRIITHPSFNDFTFDYDIALLELEKSVEYSTVVRP 749

  Fly   188 IELAGEFMHQNFLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQR--- 249
            |.|. :..|. |..||.:.::|||:..:. .....:||..:..||:|..|     ..|:.|:
Mouse   750 ICLP-DATHV-FPAGKAIWVTGWGHTKEG-GTGALILQKGEIRVINQTTC-----EDLMPQQITP 806

  Fly   250 RHLCTDG-SNGRGACNGDSGGPVVYHWRN-VSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWI 311
            |.:|... |.|..:|.||||||:....:: ..:..||.|:|  ||| :...|.||||:.....||
Mouse   807 RMMCVGFLSGGVDSCQGDSGGPLSSAEKDGRMFQAGVVSWG--EGCAQRNKPGVYTRLPVVRDWI 869

  Fly   312 RQQTAM 317
            ::.|.:
Mouse   870 KEHTGV 875

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	80/249 (32%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	81/251 (32%)
St14	XP_036010597.1	SEA	108..198	CDD:396113
		CUB	247..352	CDD:238001
		CUB	360..464	CDD:238001
		LDLa	474..506	CDD:238060
		LDLa	512..543	CDD:238060
		LDLa	545..579	CDD:238060
		LDLa	587..622	CDD:238060
		Tryp_SPc	635..872	CDD:238113	81/251 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910