DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and Mst1

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_032269.3	Gene:	Mst1 / 15235	MGIID:	96080	Length:	716	Species:	Mus musculus

Alignment Length:	308	Identity:	79/308 - (25%)
Similarity:	128/308 - (41%)	Gaps:	47/308 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SSEPWLDT------FEHPKEETPDDDD--AIMERRWQLGYENFRLRCEKFEMEGNQTAAVRTRIA 78
            |..||..|      |::...:..|||.  :|::...|:.:|    :|.|...:.|     :.|:.
Mouse   435 SHGPWCYTLDPDILFDYCALQRCDDDQPPSILDPPDQVVFE----KCGKRVDKSN-----KLRVV 490

  Fly    79 GGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDA----IAAKIYTGATVFA 139
            ||.   .|..|:.|.| ....|...  |||||:..|:||||..|:...    ...:::.| |:..
Mouse   491 GGH---PGNSPWTVSL-RNRQGQHF--CGGSLVKEQWVLTARQCIWSCHEPLTGYEVWLG-TINQ 548

  Fly   140 DVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQNFLV--G 202
            :.:.....||...    :.....|..| |.|.|::|.|.|..:..|..|.|..|    .::|  |
Mouse   549 NPQPGEANLQRVP----VAKAVCGPAG-SQLVLLKLERPVILNHHVALICLPPE----QYVVPPG 604

  Fly   203 KVVTLSGWG-YLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHLCTDG-SNGRGACNG 265
            ....::||| .:|.|.:   .:|......||..:.|...:...:  |...:||.| ....|||.|
Mouse   605 TKCEIAGWGESIGTSNN---TVLHVASMNVISNQECNTKYRGHI--QESEICTQGLVVPVGACEG 664

  Fly   266 DSGGPVVYHWRNVSYLIGVTSFGSAEGCEVGGPTVYTRITAYLPWIRQ 313
            |.|||:..:..:...|.|:. ..:........|.::||::.::.||.:
Mouse   665 DYGGPLACYTHDCWVLQGLI-IPNRVCARPRWPAIFTRVSVFVDWINK 711

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	63/242 (26%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	64/245 (26%)
Mst1	NP_032269.3	PAN_1	25..96	CDD:278453
		KR	108..188	CDD:214527
		KR	191..269	CDD:214527
		KR	291..372	CDD:214527
		KR	377..459	CDD:214527	5/23 (22%)
		Tryp_SPc	488..709	CDD:214473	63/242 (26%)
		Tryp_SPc	489..712	CDD:238113	64/245 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000