DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and Hgf

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001276387.1	Gene:	Hgf / 15234	MGIID:	96079	Length:	728	Species:	Mus musculus

Alignment Length:	284	Identity:	74/284 - (26%)
Similarity:	108/284 - (38%)	Gaps:	57/284 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 CEKFEMEGNQTAAV--------------RTRIAGGELATRGMFPYQ--VGLVIQLSGADLVKCGG 108
            |.....||:.|..:              :.|:..|       .|.|  ||.::.|...:...|||
Mouse   465 CPISRCEGDTTPTIVNLDHPVISCAKTKQLRVVNG-------IPTQTTVGWMVSLKYRNKHICGG 522

  Fly   109 SLITLQFVLTAAHCL----TDAIAAKIYTGATVFADVEDSVEE--LQVTHRDFIIYPDYLGFGGY 167
            |||...:||||..|.    .|   .|.|.......||.:..||  .|:.:...::|    |..|
Mouse   523 SLIKESWVLTARQCFPARNKD---LKDYEAWLGIHDVHERGEEKRKQILNISQLVY----GPEG- 579

  Fly   168 SDLALIRLPRKVRTSEQVQPIELAGEFMHQNFLVGKVVTLS--GWGYLG----DSTDKRTRLLQY 226
            |||.|::|.|.......|..|:|..    ....:.:..|.|  ||||.|    |.      ||:.
Mouse   580 SDLVLLKLARPAILDNFVSTIDLPS----YGCTIPEKTTCSIYGWGYTGLINADG------LLRV 634

  Fly   227 LDAEVIDQERCICYFLPGLVSQRRHLCTDGSN-GRGACNGDSGGPVVYHWRNVSYLIGVTSFGSA 290
            ....::..|:|..:....:......||..... |.|.|.||.|||::.....:..::||...|
Mouse   635 AHLYIMGNEKCSQHHQGKVTLNESELCAGAEKIGSGPCEGDYGGPLICEQHKMRMVLGVIVPG-- 697

  Fly   291 EGCEV-GGPTVYTRITAYLPWIRQ 313
            .||.: ..|.::.|:..|..||.:
Mouse   698 RGCAIPNRPGIFVRVAYYAKWIHK 721

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	68/250 (27%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	69/253 (27%)
Hgf	NP_001276387.1	PAN_APPLE	41..123	CDD:238074
		KR	127..209	CDD:214527
		KR	211..289	CDD:214527
		KR	305..385	CDD:214527
		KR	389..471	CDD:238056	1/5 (20%)
		Tryp_SPc	495..719	CDD:214473	68/250 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000