DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and F10

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	NP_001229297.1	Gene:	F10 / 14058	MGIID:	103107	Length:	493	Species:	Mus musculus

Alignment Length:	288	Identity:	82/288 - (28%)
Similarity:	132/288 - (45%)	Gaps:	37/288 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 DDDDAIMERRWQLGYENFRLRCEKFEMEGNQTAAVRT-----RIAGGELATRGMFPYQVGLVIQL 98
            |.:||:::..:....||   ..|...:  |:|...|:     ||.||.....|..|:| .|:|..
Mouse   206 DLEDALLDEDFLSPTEN---PIELLNL--NETQPERSSDDLVRIVGGRECKDGECPWQ-ALLINE 264

  Fly    99 SGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTG--ATVFADVEDSVEELQVT--HRDF--II 157
            .....  |||:::...::|||||||..|...|:..|  .|...:..:.|.|:.|.  |..|  ..
Mouse   265 DNEGF--CGGTILNEFYILTAAHCLHQARRFKVRVGDRNTEKEEGNEMVHEVDVVIKHNKFQRDT 327

  Fly   158 YPDYLGFGGYSDLALIRLPRKVRTSEQVQPIEL-AGEFMHQNFLVGKVVTLSGWGYLGDSTDKRT 221
            | ||       |:|::||...:.....|.|..| ..::.....:..|...:||:|...:. .:::
Mouse   328 Y-DY-------DIAVLRLKTPITFRMNVAPACLPQKDWAESTLMTQKTGIVSGFGRTHEK-GRQS 383

  Fly   222 RLLQYLDAEVIDQERCICYFLPGLVSQRRHLCTDGSNGR--GACNGDSGGPVVYHWRNVSYLIGV 284
            .:|:.|:...:|:..|   .|....|..:::...|...:  .||.||||||.|..::|..|:.|:
Mouse   384 NILKMLEVPYVDRNTC---KLSTSFSITQNMFCAGYEAKLEDACQGDSGGPHVTRFKNTYYVTGI 445

  Fly   285 TSFGSAEGC-EVGGPTVYTRITAYLPWI 311
            .|:|  ||| ..|...:||::|.:|.||
Mouse   446 VSWG--EGCARKGKYGIYTKVTTFLKWI 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	71/244 (29%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	72/245 (29%)
F10	NP_001229297.1	GLA	36..97	CDD:214503
		EGF_CA	98..134	CDD:238011
		FXa_inhibition	141..176	CDD:291342
		Tryp_SPc	243..471	CDD:214473	71/244 (29%)
		Tryp_SPc	244..473	CDD:238113	72/245 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000