Protein Alignment CG6462 and KLK8

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 71/245 - (28%)
• Similarity: 107/245 - (43%)
• Gaps: 21/245 - (8%)

  Fly    72 AVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGAT 136
            |...::.||........|:|..|   ..|..|: |||.|:...:|||||||.......::  |..
Human    73 AQEDKVLGGHECQPHSQPWQAAL---FQGQQLL-CGGVLVGGNWVLTAAHCKKPKYTVRL--GDH 131

  Fly   137 VFADVEDSVEELQVTHRDFIIYPDYLGF---GGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQN 198
            ...:.:...:|:.|...  |.:|.|...   ....||.|::|..:.....:|:||.||......
Human   132 SLQNKDGPEQEIPVVQS--IPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISLADHCTQP- 193

  Fly   199 FLVGKVVTLSGWGYLGDSTDKRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHLCTDGSNGRGAC 263
               |:..|:||||.:....:.....|...:.::..|::|...: ||.::... :|...|.|...|
Human   194 ---GQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAY-PGQITDGM-VCAGSSKGADTC 253

  Fly   264 NGDSGGPVVYHWRNVSYLIGVTSFGSAEGCEVGGPTVYTRITAYLPWIRQ 313
            .||||||:|..    ..|.|:||:||........|.|||.|..||.||::
Human   254 QGDSGGPLVCD----GALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKK 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	70/240 (29%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	68/237 (29%)