Protein Alignment CG6462 and PRSS21

DIOPT Version :10

• Sequence 1: NP_648011.1
• Gene: CG6462 / 38681
• FlyBaseID: FBgn0035663
• Length: 319
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 86/275 - (31%)
• Similarity: 125/275 - (45%)
• Gaps: 53/275 - (19%)

  Fly    73 VRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGATV 137
            :.:||.|||.|..|.:|:|..|.:.    |...||.||::.::.||||||.            ..
Human    38 ITSRIVGGEDAELGRWPWQGSLRLW----DSHVCGVSLLSHRWALTAAHCF------------ET 86

  Fly   138 FADVED---------------SVEELQVTH-RDFI--IY--PDYLGFGGYSDLALIRLPRKVRTS 182
            ::|:.|               |...||..: |.|:  ||  |.|||...| |:||::|...|..:
Human    87 YSDLSDPSGWMVQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRYLGNSPY-DIALVKLSAPVTYT 150

  Fly   183 EQVQPIEL-AGEFMHQNFLVGKVVTLSGWGYL-GDSTDKRTRLLQYLDAEVIDQERCICYFLPGL 245
            :.:|||.| |..|..:|   .....::||||: .|........||.:...:|:...|...||.
Human   151 KHIQPICLQASTFEFEN---RTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLK-- 210

  Fly   246 VSQRRHLCTD------GSNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGC-EVGGPTVYTR 303
            .|.|:.:..|      ...|:.||.||||||:..:...:.|.|||.|:|  .|| ....|.|||.
Human   211 YSFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWG--VGCGRPNRPGVYTN 273

  Fly   304 ITAYLPWIRQQTAMT 318
            |:.:..||::..|.:
Human   274 ISHHFEWIQKLMAQS 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	84/265 (32%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	84/264 (32%)