DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and si:dkey-32n7.7

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_021335883.1	Gene:	si:dkey-32n7.7 / 108191692	ZFINID:	ZDB-GENE-121214-179	Length:	609	Species:	Danio rerio

Alignment Length:	370	Identity:	91/370 - (24%)
Similarity:	152/370 - (41%)	Gaps:	96/370 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 QATSAFFLLLLSS-------------TLVKSSEPWLDT------FEHPKEET---PDDDDAIMER 47
            ::.|.|.::|:|.             |..:|:|...||      :..|..:.   |...:..::.
Zfish   201 ESESTFQVVLVSDKKRSFTLMHYDYITYTQSAESGYDTNGSTVFYSIPVSDVTNLPYTSNVNVKG 265

  Fly    48 RWQLGYENFRLRCEKFEMEG-----------NQTAAV--------RTRIAGGELATRGMFPYQVG 93
            ||....:|      ..|::|           :.:|||        .....||:.::...:|:|..
Zfish   266 RWVFRVDN------SSEVKGSCINTNSQALDSPSAAVCGIIPVNSSNGTVGGQNSSAVHWPWQAS 324

  Fly    94 LVIQLSGADLVKCGGSLITLQFVLTAAHC---------LTDAIAAKI---YTGATVFADVEDSVE 146
            | ...||.   .||||||..::||:||||         ||..:..|.   |..:.:...|:..::
Zfish   325 L-YWYSGQ---TCGGSLINKEWVLSAAHCFNGQRNGFYLTVILGPKTQNKYDPSRISRSVKAVIK 385

  Fly   147 ELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIELAGEFMHQNFLVGKVVT----- 206
                       :|.|......:|:||:||...:..::.::|:.||.|        |.|..
Zfish   386 -----------HPYYNPNTNDNDIALVRLSFPITFTDSIRPVCLAAE--------GSVFNSDTES 431

  Fly   207 -LSGWGYLGDSTD-KRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHLCTDG--SNGRGACNGDS 267
             ::.|..:.|... ...::.|.::..||...:|.|.:..|.::... :|. |  ..|:..|.|||
Zfish   432 WITTWRNISDGVPLPSPKIFQEVEVPVIGNRQCNCLYGVGSITDNM-ICA-GLLKEGKDLCQGDS 494

  Fly   268 GGPVVYHWRNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWI 311
            |||:|.:..:|....|:.||||  || :...|.||||::.|..||
Zfish   495 GGPMVSNQSSVWVQSGIVSFGS--GCAQSEFPGVYTRVSRYQEWI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	70/256 (27%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	72/257 (28%)
si:dkey-32n7.7	XP_021335883.1	NIDO	4..63	CDD:310601
		NIDO	141..272	CDD:322035	13/70 (19%)
		Tryp_SPc	309..537	CDD:238113	70/254 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587861
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840