DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6462 and zgc:165423

DIOPT Version :9

Sequence 1:	NP_648011.1	Gene:	CG6462 / 38681	FlyBaseID:	FBgn0035663	Length:	319	Species:	Drosophila melanogaster
Sequence 2:	XP_005164170.1	Gene:	zgc:165423 / 100101646	ZFINID:	ZDB-GENE-070720-11	Length:	538	Species:	Danio rerio

Alignment Length:	257	Identity:	78/257 - (30%)
Similarity:	120/257 - (46%)	Gaps:	33/257 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 AAVRTRIAGGELATRGMFPYQVGLVIQLSGADLVKCGGSLITLQFVLTAAHCLTDAIAAKIYTGA 135
            |.:.|:|.||..|:.|.:|:|..|  ..||:..  ||||||:.|::|:||||.........|
Zfish    32 APLNTKIVGGTNASAGSWPWQASL--HESGSHF--CGGSLISDQWILSAAHCFPSNPNPSDY--- 89

  Fly   136 TVFA-----------DVEDSVEELQVTHRDFIIYPDYLGFGGYSDLALIRLPRKVRTSEQVQPIE 189
            ||:.           :|..||.::       |::|.|.|....:|:||:.|...|..|..:||:.
Zfish    90 TVYLGRQSQDLPNPNEVSKSVSQV-------IVHPLYQGSTHDNDMALLHLSSPVTFSNYIQPVC 147

  Fly   190 LAGEFMHQNFLVGKVVTLSGWGYLGDSTD-KRTRLLQYLDAEVIDQERCICYFLPGLVSQRRHLC 253
            ||.:   .:......:.::|||.:..... ...::||.::..::....|.|.:..|.......:|
Zfish   148 LAAD---GSTFYNDTMWITGWGTIESGVSLPSPQILQEVNVPIVGNNLCNCLYGGGSSITNNMMC 209

  Fly   254 TD-GSNGRGACNGDSGGPVVYHWRNVSYLIGVTSFGSAEGC-EVGGPTVYTRITAYLPWIRQ 313
            .. ...|:.:|.||||||:|....|.....||.|||  :|| :...|.||.|::.|..||.|
Zfish   210 AGLMQGGKDSCQGDSGGPMVIKSFNTWVQAGVVSFG--KGCADPNYPGVYARVSQYQNWISQ 269

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6462	NP_648011.1	Tryp_SPc	76..311	CDD:214473	73/248 (29%)
CG6462	NP_648011.1	Tryp_SPc	77..314	CDD:238113	76/251 (30%)
zgc:165423	XP_005164170.1	Tryp_SPc	37..267	CDD:214473	73/248 (29%)
		Tryp_SPc	38..269	CDD:238113	75/249 (30%)
		Tryp_SPc	299..473	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587863
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24253
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940