DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yip7 and prss60.3

DIOPT Version :9

Sequence 1:	NP_523944.1	Gene:	yip7 / 38680	FlyBaseID:	FBgn0040060	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	243	Identity:	87/243 - (35%)
Similarity:	128/243 - (52%)	Gaps:	28/243 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 RITNGKDAVAGQFPYQVGLSFSSSAGSWWCGGSIIGNEWVLTAAHCTDGAASVT--IYYGATVRT 101
            ||..|.:|..|.:|:||.| .|...|..:||||:|.:|||||||||..|.:..|  :|.|   |.
Zfish    35 RIVGGVNASPGSWPWQVSL-HSPKYGGHFCGGSLISSEWVLTAAHCLSGVSETTLVVYLG---RR 95

  Fly   102 SPEFTQVVSSS----KFRQHESYLALTIRNDISLIQTSS-VSFSATVNKISLPAVSNSYSTYEGK 161
            :.:...:..:|    |...|.||.:.|..|||:|::.|| |:|:..:..:.|.|.::.||.  |.
Zfish    96 TQQGINIYETSRNVAKSFVHSSYNSNTNDNDIALLRLSSAVTFTNYIRPVCLAAQNSVYSA--GT 158

  Fly   162 TAVASGWGLTSDQATAVSRD----LQYVDLTIISNSKCQETFGSLIVTSRVLCVDTTNKA-STCQ 221
            ::..:|||   |....|:..    ||...:.:::|.:|....||..||:.::|...|... .|||
Zfish   159 SSWITGWG---DIQAGVNLPAPGILQETMIPVVANDRCNALLGSGTVTNNMICAGLTQGGKDTCQ 220

  Fly   222 GDSGGP----LALDGVLIGATSFGSADGC-ESGAPAAFTRITYYRDWI 264
            ||||||    |....|..|.||:|.  || :..:|..:||::.|:.||
Zfish   221 GDSGGPMVTRLCTVWVQAGITSWGY--GCADPNSPGVYTRVSQYQSWI 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yip7	NP_523944.1	Tryp_SPc	39..264	CDD:214473	85/241 (35%)
yip7	NP_523944.1	Tryp_SPc	40..267	CDD:238113	86/242 (36%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	86/242 (36%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000