DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment yip7 and CTRL

DIOPT Version :9

Sequence 1:NP_523944.1 Gene:yip7 / 38680 FlyBaseID:FBgn0040060 Length:270 Species:Drosophila melanogaster
Sequence 2:NP_001898.1 Gene:CTRL / 1506 HGNCID:2524 Length:264 Species:Homo sapiens


Alignment Length:269 Identity:97/269 - (36%)
Similarity:146/269 - (54%) Gaps:22/269 - (8%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 VVLVLALASASAGL-LPNIAPVHPRDRVSTPSITGRITNGKDAVAGQFPYQVGLSFSSSAGSWWC 68
            :.|.|.|..:|.|. :|.|.|        ..|.:.||.||::||.|.:|:||  |...|:|..:|
Human     6 LTLSLVLLGSSWGCGIPAIKP--------ALSFSQRIVNGENAVLGSWPWQV--SLQDSSGFHFC 60

  Fly    69 GGSIIGNEWVLTAAHCTDGAASVTIYYGATVRTS-PEFTQVVSSSKFRQHESYLALTIRNDISLI 132
            |||:|...||:|||||........:..|...|:| .|..||:|.|:...|.|:.:.|:.||::|:
Human    61 GGSLISQSWVVTAAHCNVSPGRHFVVLGEYDRSSNAEPLQVLSVSRAITHPSWNSTTMNNDVTLL 125

  Fly   133 QTSS-VSFSATVNKISLPAVSNSYSTYEGKTAVASGWGLTSDQATAVSRDLQYVDLTIISNSKCQ 196
            :.:| ..::..::.:.| |.||...| ||.|.|.:|||..|.........||.|.|.:::.::|:
Human   126 KLASPAQYTTRISPVCL-ASSNEALT-EGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQCR 188

  Fly   197 ETFGSLIVTSRVLCVDTTNKASTCQGDSGGPLALD----GVLIGATSFGSADGCESGAPAAFTRI 257
            :.:||.| |..::|..... ||:|||||||||...    .||||..|:|:.: |...|||.:||:
Human   189 QYWGSSI-TDSMICAGGAG-ASSCQGDSGGPLVCQKGNTWVLIGIVSWGTKN-CNVRAPAVYTRV 250

  Fly   258 TYYRDWIKE 266
            :.:..||.:
Human   251 SKFSTWINQ 259

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
yip7NP_523944.1 Tryp_SPc 39..264 CDD:214473 86/230 (37%)
Tryp_SPc 40..267 CDD:238113 87/233 (37%)
CTRLNP_001898.1 Tryp_SPc 34..260 CDD:238113 87/233 (37%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1522379at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X11
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.920

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