DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10477 and Cela3b

DIOPT Version :9

Sequence 1:	NP_001303385.1	Gene:	CG10477 / 38679	FlyBaseID:	FBgn0035661	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_080695.1	Gene:	Cela3b / 67868	MGIID:	1915118	Length:	269	Species:	Mus musculus

Alignment Length:	278	Identity:	89/278 - (32%)
Similarity:	137/278 - (49%)	Gaps:	38/278 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 AVLVLAIATVSADILRQDTPVHPRDSSAVPSIDGRITNGNKAAANQFPYQVGLSFKSSAGSW--W 67
            ::|::|:|:....      |.|...|        |:.||.:|..:.:|:||.|.::.. ||:  .
Mouse     7 SLLLVALASGCGQ------PSHNPSS--------RVVNGEEAVPHSWPWQVSLQYEKD-GSFHHT 56

  Fly    68 CGGSIIANTWVLTAAHCTKGASSVTIYYGSTVRTSAKLKKKV----SSSKFVQHAGYNA--ATLR 126
            ||||:|...|||||.||...:.:..:..|...|...:.:::|    :...|| |..:|:  .:..
Mouse    57 CGGSLITPDWVLTAGHCISTSRTYQVVLGEHERGVEEGQEQVIPINAGDLFV-HPKWNSMCVSCG 120

  Fly   127 NDISLIK-TPSVTFTVSINKIALPAIASSYSTYAGQTAVASGWGRTSDSSIAVATNLQYAQFQVI 190
            |||:|:| :.|.....::....||........  |.....|||||.|.:. .:...||.|...|:
Mouse   121 NDIALVKLSRSAQLGDAVQLACLPPAGEILPN--GAPCYISGWGRLSTNG-PLPDKLQQALLPVV 182

  Fly   191 TNAVCQK--TFGSSVVTSGVICVESINKKSTCQGDSGGPL---ALNN--RLIGVTSFVSSKGCEK 248
            ....|.:  .:|.||.|: ::|... :.:|.|.|||||||   |.|.  ::.||||||||.||..
Mouse   183 DYEHCSRWNWWGLSVKTT-MVCAGG-DIQSGCNGDSGGPLNCPADNGTWQVHGVTSFVSSLGCNT 245

  Fly   249 -NAPAGFTRVTSYLDWIK 265
             ..|..||||::::|||:
Mouse   246 LRKPTVFTRVSAFIDWIE 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10477	NP_001303385.1	Tryp_SPc	39..264	CDD:214473	81/241 (34%)
CG10477	NP_001303385.1	Tryp_SPc	40..267	CDD:238113	82/243 (34%)
Cela3b	NP_080695.1	Tryp_SPc	27..262	CDD:214473	81/241 (34%)
Cela3b	NP_080695.1	Tryp_SPc	28..265	CDD:238113	82/243 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	147	1.000	Inparanoid score	I4390
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960