DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10477 and Ctrb1

DIOPT Version :9

Sequence 1:	NP_001303385.1	Gene:	CG10477 / 38679	FlyBaseID:	FBgn0035661	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_079859.2	Gene:	Ctrb1 / 66473	MGIID:	88559	Length:	263	Species:	Mus musculus

Alignment Length:	278	Identity:	85/278 - (30%)
Similarity:	136/278 - (48%)	Gaps:	39/278 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FAVLVLAIATVSADILRQDTPVHPRDSSAVPSID------GRITNGNKAAANQFPYQVGLSFKSS 62
            |..||...|.|.|..           ...||:|.      .||.||..|....:|:||  |.:..
Mouse     3 FLWLVSCFALVGATF-----------GCGVPAIQPVLTGLSRIVNGEDAIPGSWPWQV--SLQDR 54

  Fly    63 AGSWWCGGSIIANTWVLTAAHCTKGASSVTIY----YGSTVRTSAKLKKKVSSSKFVQHAGYNAA 123
            .|..:||||:|:..||:|||||....:.|.:.    .||.......||    .::..::..:|:.
Mouse    55 TGFHFCGGSLISENWVVTAAHCGVKTTDVVVAGEFDQGSDEENVQVLK----IAQVFKNPKFNSF 115

  Fly   124 TLRNDISLIK--TPSVTFTVSINKIALPAIASSYSTYAGQTAVASGWGRTSDSSIAVATNLQYAQ 186
            |:||||:|:|  ||: .|:.:::.:.||.:...:.  ||.....:|||:|..:::.....||.|.
Mouse   116 TVRNDITLLKLATPA-QFSETVSAVCLPTVDDDFP--AGTLCATTGWGKTKYNALKTPDKLQQAA 177

  Fly   187 FQVITNAVCQKTFGSSVVTSGVICVESINKKSTCQGDSGGPLALNN----RLIGVTSFVSSKGCE 247
            ..:::.|.|::::||. :|..:||. ..:..|:|.|||||||....    .|.|:.|: .|..|.
Mouse   178 LPIVSEAKCKESWGSK-ITDVMICA-GASGVSSCMGDSGGPLVCQKDGVWTLAGIVSW-GSGFCS 239

  Fly   248 KNAPAGFTRVTSYLDWIK 265
            .:.||.:.|||:.:.|::
Mouse   240 TSTPAVYARVTALMPWVQ 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10477	NP_001303385.1	Tryp_SPc	39..264	CDD:214473	75/234 (32%)
CG10477	NP_001303385.1	Tryp_SPc	40..267	CDD:238113	75/236 (32%)
Ctrb1	NP_079859.2	Tryp_SPc	33..256	CDD:214473	75/234 (32%)
Ctrb1	NP_079859.2	Tryp_SPc	34..259	CDD:238113	75/236 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	147	1.000	Inparanoid score	I4390
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960