DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10477 and CG18754

DIOPT Version :9

Sequence 1:	NP_001303385.1	Gene:	CG10477 / 38679	FlyBaseID:	FBgn0035661	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	269	Identity:	66/269 - (24%)
Similarity:	107/269 - (39%)	Gaps:	55/269 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 QDTPVHPRDSSAVPSIDGRITNGNKAAANQFPYQVGLSFKSSAGSWWCGGSIIANTWVLTAAHCT 85
            |.|||. ||..|           ..|..|::|:.|.|.:::..       |:|  .:|||||||.
  Fly    99 QTTPVF-RDRGA-----------ENAELNEYPWMVLLLYENRL-------SLI--RYVLTAAHCV 142

  Fly    86 KGA---------SSVTIYYGSTVRTSAKLK---KKVSSSKFVQHAGYNAA--TLRNDISLIKTP- 135
            .|.         .||.:...:|...:::.:   ..|...:...|.|:.::  |.||||:|::..
  Fly   143 IGGYLTQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSGGTYRNDIALLRLQF 207

  Fly   136 SVTFTVSINKIALPAIASSYSTYAGQTAVASGWGRTSDSSIAVATNLQYAQFQVITNAVCQKTFG 200
            .|.:|..|..|.|  :.:.:........: |||..|..|...:.:.::..     ..|.|...:
  Fly   208 PVRYTKKIQPICL--LDAEFPLQDLNLQI-SGWDPTKSSQTLITSTVKER-----NPADCLNRY- 263

  Fly   201 SSVVTSGVICVESINKKSTCQGDSGGPLALNNRLIGVTSFVSSKG--------C-EKNAPAGFTR 256
            .|..::..:|.....|..||.|.||.|: :.....||..||...|        | ....|..:|:
  Fly   264 PSFRSASQVCAGGQRKGDTCAGISGSPV-MGIMGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTK 327

  Fly   257 VTSYLDWIK 265
            :..:.:|||
  Fly   328 IGHFSEWIK 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10477	NP_001303385.1	Tryp_SPc	39..264	CDD:214473	56/248 (23%)
CG10477	NP_001303385.1	Tryp_SPc	40..267	CDD:238113	59/250 (24%)
CG18754	NP_652652.3	CLIP	35..84	CDD:288855
		Tryp_SPc	108..338	CDD:238113	60/259 (23%)
		Tryp_SPc	108..335	CDD:214473	57/256 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436185
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030