Protein Alignment CG10477 and TMPRSS4

DIOPT Version :10

• Sequence 1: NP_648010.1
• Gene: CG10477 / 38679
• FlyBaseID: FBgn0035661
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: XP_005271670.1
• Gene: TMPRSS4 / 56649
• HGNCID: 11878
• Length: 494
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 74/294 - (25%)
• Similarity: 118/294 - (40%)
• Gaps: 72/294 - (24%)

  Fly    17 DILRQDTPVHPRDSSAVPSIDG-----------------RITNGNKAAANQFPYQVGLSFKSSAG 64
            :|......:..|:||. |.:.|                 |:....:|:.:.:|:||.:.:..
Human   166 EITENSQELRMRNSSG-PCLSGSLVSLHCLACGKSLKTPRVVGVEEASVDSWPWQVSIQYDK--- 226

  Fly    65 SWWCGGSIIANTWVLTAAHCTKGASSVTIYYGSTVRTSAKLKKKVSSSKFVQHAGYNAATL---- 125
            ...|||||:...||||||||.:..:.|..:           |.:..|.|.........|.:
Human   227 QHVCGGSILDPHWVLTAAHCFRKHTDVFNW-----------KVRAGSDKLGSFPSLAVAKIIIIE 280

  Fly   126 -------RNDISLIKTP-SVTFTVSINKIALPAIASSYSTYAGQTAVASGWGRTSDSSIAVATNL 182
                   .|||:|:|.. .:||:.::..|.||......:.......:  |||.|..:...::..|
Human   281 FNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDEELTPATPLWII--GWGFTKQNGGKMSDIL 343

  Fly   183 QYAQFQVITNAVC-----------QKTFGSSVVTSGVICVESINKKSTCQGDSGGPLALNN---R 233
            ..|..|||.:..|           :|...:.:...||         .||||||||||...:   .
Human   344 LQASVQVIDSTRCNADDAYQGEVTEKMMCAGIPEGGV---------DTCQGDSGGPLMYQSDQWH 399

  Fly   234 LIGVTSFVSSKGC-EKNAPAGFTRVTSYLDWIKN 266
            ::|:.|:  ..|| ..:.|..:|:|::||:||.|
Human   400 VVGIVSW--GYGCGGPSTPGVYTKVSAYLNWIYN 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10477	NP_648010.1	Tryp_SPc	39..264	CDD:214473	65/251 (26%)
TMPRSS4	XP_005271670.1	LDLa	58..92	CDD:238060
		SRCR_2	108..197	CDD:470597	6/31 (19%)
		Tryp_SPc	204..429	CDD:214473	65/251 (26%)