Protein Alignment CG10477 and KLK12

DIOPT Version :10

• Sequence 1: NP_648010.1
• Gene: CG10477 / 38679
• FlyBaseID: FBgn0035661
• Length: 272
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 72/235 - (30%)
• Similarity: 112/235 - (47%)
• Gaps: 21/235 - (8%)

  Fly    31 SAVPSIDGRITNGNKAAANQFPYQVGLSFKSSAGSWWCGGSIIANTWVLTAAHCTKGASSVTIYY 95
            :|.|    :|.||.:...|..|:|||| |:.:  |..|||.:|.:.||||||||:  .|...:..
Human    17 AATP----KIFNGTECGRNSQPWQVGL-FEGT--SLRCGGVLIDHRWVLTAAHCS--GSRYWVRL 72

  Fly    96 GSTVRTSAKLKKKVSSSKF-VQHAGYNAATL--RNDISLIKTP-SVTFTVSINKIALPAIASSYS 156
            |....:.....:::..|.| |.|.||..|:.  .:|:.|::.. .|..|.|:..:.||...::
Human    73 GEHSLSQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLRLPVRVTSSVQPLPLPNDCAT-- 135

  Fly   157 TYAGQTAVASGWGRTSDSSIAVATNLQYAQFQVITNAVCQKTFGSSVVTSGVICVESINKKSTCQ 221
              ||.....||||.|:.........||.....::::|.|...:... :||.::|...:..:..||
Human   136 --AGTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVYPGR-ITSNMVCAGGVPGQDACQ 197

  Fly   222 GDSGGPLALNNRLIGVTSFVSSKGCEKNAPAGFTRVTSYL 261
            |||||||.....|.|:.|:.|...|.::   |...|.:|:
Human   198 GDSGGPLVCGGVLQGLVSWGSVGPCGQD---GIPGVYTYI 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10477	NP_648010.1	Tryp_SPc	39..264	CDD:214473	70/227 (31%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	70/226 (31%)