DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10477 and modSP

DIOPT Version :9

Sequence 1:	NP_001303385.1	Gene:	CG10477 / 38679	FlyBaseID:	FBgn0035661	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster

Alignment Length:	266	Identity:	62/266 - (23%)
Similarity:	100/266 - (37%)	Gaps:	79/266 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 PYQVGLSFKSSAGSWW---------CGGSIIANTWVLTAAHCTKGASSVTIYYGSTVRT-SAKL- 105
            |:.|||..       |         ||||::....|:|||||.....:...|...|.|. :||.
  Fly   381 PWHVGLYV-------WHNEKDYHFQCGGSLLTPDLVITAAHCVYDEGTRLPYSYDTFRVIAAKFY 438

  Fly   106 --------KKKVSSSKFVQHA-GYNAAT--LRNDISLIKTPSVTFTVSINKIALPAIASSYSTYA 159
                    ::|....:.::.| ||...|  ...|::|: |....|.:|  .:..| |..:::::|
  Fly   439 RNYGETTPEEKRRDVRLIEIAPGYKGRTENYYQDLALL-TLDEPFELS--HVIRP-ICVTFASFA 499

  Fly   160 GQTAVA-------SGWGRTSDSSIAVATNLQYAQFQVITNAVCQKTFGSSVVTSGVICVESINKK 217
            .:.:|.       :||      :|.....||:......:|:||::....  :.:...|:.:..|.
  Fly   500 EKESVTDDVQGKFAGW------NIENKHELQFVPAVSKSNSVCRRNLRD--IQADKFCIFTQGKS 556

  Fly   218 STCQGDSGGPLALNNRLIGVTSFVSSK-------------GCEKNAPAG---------FTRVTSY 260
            ..|||||||         |.||.:.:.             |...|||..         .|.:..:
  Fly   557 LACQGDSGG---------GFTSELPTNAFSTWNTARHFLFGVISNAPNADQCAHSLTVMTNIQHF 612

  Fly   261 LDWIKN 266
            .|.|.|
  Fly   613 EDMILN 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10477	NP_001303385.1	Tryp_SPc	39..264	CDD:214473	60/262 (23%)
CG10477	NP_001303385.1	Tryp_SPc	40..267	CDD:238113	62/266 (23%)
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512
		Tryp_SPc	371..616	CDD:214473	60/262 (23%)
		Tryp_SPc	371..591	CDD:304450	55/237 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436854
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030