Protein Alignment PVRAP and tns1a

DIOPT Version :10

• Sequence 1: NP_729124.1
• Gene: PVRAP / 38677
• FlyBaseID: FBgn0052406
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: XP_073810067.1
• Gene: tns1a / 565181
• ZFINID: ZDB-GENE-120215-32
• Length: 1688
• Species: Danio rerio
• Alignment Length: 646
• Identity: 135/646 - (20%)
• Similarity: 224/646 - (34%)
• Gaps: 218/646 - (33%)

  Fly     2 PKSEAATMITNNNLDYDQASASSTIIAGATSTTAGTAA--TSVAMSNRNGSTSSSSNSSP----- 59
            |||| ..|:....|...:.:..:..|.|.:.:.:..:.  .|.:.|..:..|.:...:.|
Zfish   962 PKSE-EEMLNLEGLVAHRVAEYNARIRGISKSMSFQSEHHRSYSFSGSHSRTVTPDEAMPTVRRR 1025

  Fly    60 -TADNSNSNSNSNSNANINRN------------LNQNPNSNSNTNS-NSYFNRFDNRIAANLA-- 108
             |:::...:|..:|.|::.|:            :..||.......| :||...|:...:|..:
Zfish  1026 TTSESQYLSSQHDSAAHVVRSPLKPVSPEFANTITMNPGGQPKEKSVHSYREAFEEMESAPFSSA 1090

  Fly   109 ---------AVLTGAGARFRS--------------SSCSNRHPAGVANPAV--------LRSPLA 142
                     |.|:.||.|.::              ||.....|.|.....:        |..|.:
Zfish  1091 HDNAGLSGQATLSAAGLRAQNPAEALVQQNSSDSDSSDEMEEPHGFVGTGIREGGFISPLHHPYS 1155

  Fly   143 TISRK----TSLATPPSPAS------LGRRR------------PLQLFTHANLNCNDNE----KV 181
            :.|.:    ....:||.|.:      .|.:|            ||.|.|.:.||.::..    .:
Zfish  1156 SASERPVPPAHTFSPPQPVNNTSSDGFGNQRAFPSFPSEPIRAPLFLDTFSYLNPDEATVNIMGI 1220

  Fly   182 AQTPSSDE-------DNSPTELNSCKRLA--DKPPLVKRLTMGLLRQNEESR------PLVG--- 228
            ...|.|..       .|:|......:||.  ..|...:|:|..    |..|.      ||:|
Zfish  1221 HHVPGSPNTLHRTVATNTPPSPALQRRLGGPSSPAFGRRITTA----NSGSEPTTPNSPLLGRSG 1281

  Fly   229 ---------DMTPLSAPLDIQP---VYSNGYINEDSYIDSKFGDSCRQSLT-------AIPMLDN 274
                     |..|..||:...|   |...|....    |.:.|...|||:|       |.|
Zfish  1282 KFIPPSPVLDRHPSPAPVASSPDHKVLPRGQATP----DERHGAQSRQSITSTVQPGHATP---- 1338

  Fly   275 VNLNDNNEFNLKKRYLRETSSANSSPKIFANRLRMNQGAVGQRCSSLAN---------------- 323
                   .|.:::         :|||.:|. .|.:..|      ||:.|
Zfish  1339 -------TFPIEQ---------SSSPSLFL-PLDIRAG------SSMENSESGPADCGPTQVPPQ 1380

  Fly   324 --AFGNVGSDEEDLELK-------DACWYQAGISRDIAVEVLQSKSPGAFLVRKSSSKPGCYALT 379
              |..::.....|:.:.       ...||:..|:|:.|:.:|:.:.||||::|.|:|..|.|.|.
Zfish  1381 GPAITSIYDGPPDIRINIKFVQDTSKYWYKPEITREQAICILKDREPGAFVIRDSNSFRGAYGLA 1445

  Fly   380 LRVPSPP-------------GPKIANYIILRSPRGYKIKGFRKE--FSSLKALITHHSVMPELLP 429
            ::|.|||             ...:.:::|..|.:|.::||...|  |..|.||:..|::.|..||
Zfish  1446 MKVASPPPTVQQNKKVGDITNELVRHFLIETSAKGVRLKGCPNEPYFGCLSALVYQHAITPLALP 1510

  Fly   430 VPLAMP-RPTN--------MSSSRRNL-----------DDFDTYDSLQMLLKYLRAKNMET 470
            ..|.:| |..|        .:||..:|           :||...:.|     |:.:.:||:
Zfish  1511 CKLMIPTRDPNEEALELATPTSSTMDLLKQGAGPPKPTEDFYACNVL-----YINSVDMES 1566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PVRAP	NP_729124.1	SH2	342..435	CDD:472789	35/107 (33%)
tns1a	XP_073810067.1	None