Protein Alignment alphaKap4 and kpna2

DIOPT Version :10

• Sequence 1: NP_648007.1
• Gene: alphaKap4 / 38675
• FlyBaseID: FBgn0035657
• Length: 442
• Species: Drosophila melanogaster
• Sequence 2: NP_001002335.1
• Gene: kpna2 / 436607
• ZFINID: ZDB-GENE-040718-22
• Length: 525
• Species: Danio rerio
• Alignment Length: 489
• Identity: 130/489 - (26%)
• Similarity: 226/489 - (46%)
• Gaps: 65/489 - (13%)

  Fly     4 RKRRFLKKGQNLMMLRTLRLE------KAKKAE------------------LQK----------- 33
            |..:|..||::...||..|:|      ||||.|                  ||:
Zfish    10 RLTQFKNKGKDATELRRRRIEVNVELRKAKKDEQILKRRNVSSFPDEATSPLQEKSQNCQAQHWT 74

  Fly    34 -------------ELTIYNALTKCKLTSSEVVPDVNKLLKSNTIGNLVESLGHGNKNKIRADAAD 85
                         |..:.......||.|.|..|.:::::.:..|...|..|...:...|:.:||.
Zfish    75 VEEIVNGVNSNNLETQVQATQAARKLLSRERHPPIDRIISAGLIPKFVGFLSLVDSPPIQFEAAW 139

  Fly    86 ALAHIASGSSEHSNLIAKAGAVPRLIRLLQSPDPEVCEKGILSLGNLLHFAPNLRDYIIRHGLMQ 150
            ||.:||||:|:.::.:.:.||:|..|.|:.||...:.|:.:.:|||:.......||.:|:||.:.
Zfish   140 ALTNIASGTSDQTSAVVQGGAIPAFISLISSPHAHISEQAVWALGNIAGDGSGYRDRVIKHGAIP 204

  Fly   151 KLMSI--IQDKSTCTL-MLSHVTWVLRKLCISSQPSPPDNAA-EIIQALNIVLYNPEANVLEDAL 211
            .|:::  :.|.|.... .|.:|||.|..||.:..|:||..|. :|:..|..:|.:.:..||.|..
Zfish   205 PLLALLAVPDLSVFPAGYLRNVTWTLSNLCRNKNPAPPLEAVKQILPTLICLLQHSDKEVLADTC 269

  Fly   212 MAVRNLAHG-NETIQMLLDFEVVPRIIYLLEHPNVTVQNAALQALINIATGSEEQIQELLNNNLL 275
            .|:..|..| |:.|:::::..||||::.||....:::...:|:::.||.||::||.|.:|....|
Zfish   270 WAISYLTDGPNDRIEVVVNAGVVPRLVQLLASGELSIVTPSLRSIGNIVTGTDEQTQAVLEAGAL 334

  Fly   276 PHLSALMSNSDPDIRCQVLKLLLNIADGNIFQRHAIMNAGLLHKILECLKADAISLKSAAALTIT 340
            |...||:.:...:|:.:....|.||..|..:|...::|||::..::|.|:......:..|...:|
Zfish   335 PMFPALLRHQKSNIQKEASWTLSNITAGRDYQIQEVINAGIVPYLVEVLRRGDYKTQKEAVWAVT 399

  Fly   341 TLAIDKDKNLLCYLMRQGVIPEFCNLLFCQERDILSNVLDILSTMLDVDPSFSAEVSG------- 398
            ..........:.||::..|:....|||..::...:..:||.::.:.     .:.|..|
Zfish   400 NYTSGGTVEQVVYLVQANVLEPLLNLLSTKDSTTILVILDAITNIF-----LAGEKIGEVEKLCL 459

  Fly   399 IIEWSGALNNIRMLQSSEHEEIAAVARKIIGNYF 432
            :||..|.|:.|..|||.|:|.:...:..:|..||
Zfish   460 MIEECGGLDKIEALQSHENEMVYKASLNLIEKYF 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaKap4	NP_648007.1	SRP1	45..432	CDD:227396	112/398 (28%)
		armadillo repeat	98..134	CDD:293788	11/35 (31%)
		armadillo repeat	140..176	CDD:293788	13/38 (34%)
		armadillo repeat	192..217	CDD:293788	6/24 (25%)
		armadillo repeat	224..260	CDD:293788	10/35 (29%)
		armadillo repeat	266..300	CDD:293788	8/33 (24%)
		armadillo repeat	308..342	CDD:293788	7/33 (21%)
		armadillo repeat	350..383	CDD:293788	8/32 (25%)
kpna2	NP_001002335.1	SRP1	9..525	CDD:227396	130/489 (27%)
		armadillo repeat	112..144	CDD:293788	8/31 (26%)
		armadillo repeat	152..188	CDD:293788	11/35 (31%)
		armadillo repeat	194..233	CDD:293788	13/38 (34%)
		armadillo repeat	250..275	CDD:293788	6/24 (25%)
		armadillo repeat	283..319	CDD:293788	10/35 (29%)
		armadillo repeat	325..359	CDD:293788	8/33 (24%)
		armadillo repeat	367..403	CDD:293788	7/35 (20%)
		armadillo repeat	410..444	CDD:293788	8/33 (24%)
		armadillo repeat	452..492	CDD:293788	12/39 (31%)