Protein Alignment alphaKap4 and Kpna4

DIOPT Version :10

• Sequence 1: NP_648007.1
• Gene: alphaKap4 / 38675
• FlyBaseID: FBgn0035657
• Length: 442
• Species: Drosophila melanogaster
• Sequence 2: NP_001014793.1
• Gene: Kpna4 / 361959
• RGDID: 1311483
• Length: 521
• Species: Rattus norvegicus
• Alignment Length: 477
• Identity: 160/477 - (33%)
• Similarity: 252/477 - (52%)
• Gaps: 48/477 - (10%)

  Fly     3 KRKRRFLKKGQNLMMLRTLR------LEKAKKAE--LQK-------------------------E 34
            :|.:.|..||::|..:|..|      |.|.|:.|  |::                         |
  Rat    10 QRLKNFKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPQEDICEDSDIDGDYRVQNTSLE 74

  Fly    35 LTIYNALT------------KCKLTSSEVVPDVNKLLKSNTIGNLVESLGHGNKNKIRADAADAL 87
            ..:.||.:            ..||.||:..|.::.|:||..:..||..|...:...::.:||.||
  Rat    75 AIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWAL 139

  Fly    88 AHIASGSSEHSNLIAKAGAVPRLIRLLQSPDPEVCEKGILSLGNLLHFAPNLRDYIIRHGLMQKL 152
            .:||||:||.:..:.::.|||..:|||.||...|||:.:.:|||::...|..|||:|..|:::.|
  Rat   140 TNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPL 204

  Fly   153 MSIIQDKSTCTLMLSHVTWVLRKLCISSQPSPP-DNAAEIIQALNIVLYNPEANVLEDALMAVRN 216
            :|.|......| .|.:||||:..||....|.|| :...||:.||.:::::.:.|:|.|.:.|:..
  Rat   205 LSFISPSIPIT-FLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSY 268

  Fly   217 LAH-GNETIQMLLDFEVVPRIIYLLEHPNVTVQNAALQALINIATGSEEQIQELLNNNLLPHLSA 280
            |.. |||.|||::|..:||.::.||.|..|.||.|||:|:.||.||::||.|.:||.:.|.|..|
  Rat   269 LTDAGNEQIQMVIDSGIVPHLVPLLSHQEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPA 333

  Fly   281 LMSNSDPDIRCQVLKLLLNIADGNIFQRHAIMNAGLLHKILECLKADAISLKSAAALTITTLAID 345
            |:::....|..:.:..|.||..||..|..|:::|.|:..|:..|.......:..||..|:.|.|.
  Rat   334 LLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTIS 398

  Fly   346 KDKNLLCYLMRQGVIPEFCNLLFCQERDILSNVLDILSTMLDVDPSFSAEVSGIIEWSGALNNIR 410
            ..|:.:.||::|.|||.|||||..::..::..|||.||.:|.:....:..::.:||..|.|..|.
  Rat   399 GRKDQVAYLIQQNVIPPFCNLLTVKDAQVVQVVLDGLSNILKMAEDQAETIANLIEECGGLEKIE 463

  Fly   411 MLQSSEHEEIAAVARKIIGNYF 432
            .||:.|:|:|..:|.:||..:|
  Rat   464 QLQNHENEDIYKLAYEIIDQFF 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaKap4	NP_648007.1	SRP1	45..432	CDD:227396	144/388 (37%)
		armadillo repeat	98..134	CDD:293788	14/35 (40%)
		armadillo repeat	140..176	CDD:293788	14/35 (40%)
		armadillo repeat	192..217	CDD:293788	6/24 (25%)
		armadillo repeat	224..260	CDD:293788	18/35 (51%)
		armadillo repeat	266..300	CDD:293788	9/33 (27%)
		armadillo repeat	308..342	CDD:293788	8/33 (24%)
		armadillo repeat	350..383	CDD:293788	14/32 (44%)
Kpna4	NP_001014793.1	SRP1	11..513	CDD:227396	160/476 (34%)
		armadillo repeat	73..98	CDD:293788	3/24 (13%)
		armadillo repeat	109..142	CDD:293788	10/32 (31%)
		armadillo repeat	150..186	CDD:293788	14/35 (40%)
		armadillo repeat	192..227	CDD:293788	14/35 (40%)
		armadillo repeat	244..269	CDD:293788	6/24 (25%)
		armadillo repeat	279..311	CDD:293788	14/31 (45%)
		armadillo repeat	319..355	CDD:293788	11/35 (31%)
		armadillo repeat	361..395	CDD:293788	8/33 (24%)
		armadillo repeat	404..438	CDD:293788	16/33 (48%)