Protein Alignment alphaKap4 and Pen

DIOPT Version :10

• Sequence 1: NP_648007.1
• Gene: alphaKap4 / 38675
• FlyBaseID: FBgn0035657
• Length: 442
• Species: Drosophila melanogaster
• Sequence 2: NP_477041.1
• Gene: Pen / 34338
• FlyBaseID: FBgn0287720
• Length: 522
• Species: Drosophila melanogaster
• Alignment Length: 478
• Identity: 123/478 - (25%)
• Similarity: 221/478 - (46%)
• Gaps: 87/478 - (18%)

  Fly    20 TLRLEKAKK------------AELQKELTIYNALTKCKLTSSEVVPDVN---------------K 57
            |:.|.|:||            .:|...|...|..:..:|:..|:|..:|               |
  Fly    31 TIELRKSKKEDQMFKRRNINDEDLTSPLKELNGQSPVQLSVDEIVAAMNSEDQERQFLGMQSARK 95

  Fly    58 LLKSNTIGNLVESLGHG------------NKNKIRADAADALAHIASGSSEHSNLIAKAGAVPRL 110
            :|.......:...:|||            |.:.::.:||.||.:||||:|:.:..:.:..|||..
  Fly    96 MLSRERNPPIDLMIGHGIVPICIRFLQNTNNSMLQFEAAWALTNIASGTSDQTRCVIEHNAVPHF 160

  Fly   111 IRLLQSPDPEVCEKGILSLGNLLHFAPNLRDYIIRHGLMQKLMSIIQDKSTCTLMLSHVTWVLRK 175
            :.||||....:.|:.:.:|||:.......||.:|.|.::..::.:|.:::..: .|.::.|::..
  Fly   161 VALLQSKSMNLAEQAVWALGNIAGDGAAARDIVIHHNVIDGILPLINNETPLS-FLRNIVWLMSN 224

  Fly   176 LCISSQPSPP-DNAAEIIQALNIVLYNPEANVLEDALMAVRNLAHGNET-IQMLLDFEVVPRIIY 238
            ||.:..|||| |....::..|:.:|.:.:..||.||..|:..:...:.| ||.::|.:.|||::.
  Fly   225 LCRNKNPSPPFDQVKRLLPVLSQLLLSQDIQVLADACWALSYVTDDDNTKIQAVVDSDAVPRLVK 289

  Fly   239 LLEHPNVTVQNAALQALINIATGSEEQIQELLNNNLLPHLSALMSNSDPDIRCQVLKLLLNIADG 303
            ||:....::...||:::.||.||:::|...::.:..||.|..|:.::..:|..:....:.||..|
  Fly   290 LLQMDEPSIIVPALRSVGNIVTGTDQQTDVVIASGGLPRLGLLLQHNKSNIVKEAAWTVSNITAG 354

  Fly   304 NIFQRHAIMNAGL---LHKILECLKADAISLKSAA-ALTITTLAIDKDKNLLCYLMRQGVIPEFC 364
            |..|..|::.||:   |..:||  |.|..:.|.|| |:|.||.:              |...:..
  Fly   355 NQKQIQAVIQAGIFQQLRTVLE--KGDFKAQKEAAWAVTNTTTS--------------GTPEQIV 403

  Fly   365 NLLFCQERDILSNVLDILSTMLDVDP--------------SFSAEVSG------IIEWSGALNNI 409
            :|:  ::..||...:|:|.|.   ||              :.:.::.|      ::|..|.|:.:
  Fly   404 DLI--EKYKILKPFIDLLDTK---DPRTIKVVQTGLSNLFALAEKLGGTENLCLMVEEMGGLDKL 463

  Fly   410 RMLQSSEHEEIAAVARKIIGNYF 432
            ..||..|:||:...|..||..||
  Fly   464 ETLQQHENEEVYKKAYAIIDTYF 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaKap4	NP_648007.1	SRP1	45..432	CDD:227396	113/439 (26%)
		armadillo repeat	98..134	CDD:293788	11/35 (31%)
		armadillo repeat	140..176	CDD:293788	7/35 (20%)
		armadillo repeat	192..217	CDD:293788	7/24 (29%)
		armadillo repeat	224..260	CDD:293788	12/35 (34%)
		armadillo repeat	266..300	CDD:293788	5/33 (15%)
		armadillo repeat	308..342	CDD:293788	14/37 (38%)
		armadillo repeat	350..383	CDD:293788	5/32 (16%)
Pen	NP_477041.1	SRP1	2..517	CDD:227396	123/478 (26%)
		HEAT repeat	70..102	CDD:293787	5/31 (16%)
		armadillo repeat	108..140	CDD:293788	8/31 (26%)
		armadillo repeat	148..184	CDD:293788	11/35 (31%)
		armadillo repeat	190..225	CDD:293788	7/35 (20%)
		armadillo repeat	359..396	CDD:293788	15/38 (39%)
		armadillo repeat	402..437	CDD:293788	8/39 (21%)