DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alphaKap4 and AT5G49305

DIOPT Version :9

Sequence 1:	NP_648007.1	Gene:	alphaKap4 / 38675	FlyBaseID:	FBgn0035657	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_001331293.1	Gene:	AT5G49305 / 28721258	AraportID:	AT5G49305	Length:	384	Species:	Arabidopsis thaliana

Alignment Length:	381	Identity:	93/381 - (24%)
Similarity:	164/381 - (43%)	Gaps:	56/381 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 LLKSNTIGNLVESLGHGNKNKIRADAADALAHIASGSSEHSNLIAKAGAVPRLIRLLQSPDPEVC 122
            |::|..:...|..|.:....|::.:||..||.||:...:   ::.....||.|:.||.|....|.
plant    41 LIRSGIVARFVFLLHNEEFPKLQFEAARGLAIIAAFKPD---VVVDHKVVPILVTLLASSTDNVR 102

  Fly   123 EKGILSLGNLLHFAPNLRDYIIRHGLMQKLMSIIQDKSTCTLMLSHVTWVLRKLCISSQPSPPDN 187
            .:.||:|||:. :.|..|||:::.|.:..|: |...|.|...||......|..||   :..||..
plant   103 GQAILALGNVA-YHPIHRDYVLQCGALTPLL-IRLYKDTNLPMLRAAIRTLAFLC---RGMPPST 162

  Fly   188 AAEIIQALNIVLYNPEANVLEDALMAVRNLAHGN-ETIQMLLDFEVVPRIIYLLEHPNVTVQNAA 251
            ..|:..||.|.|.:.:..:|....:|:.:|.:|: :.||.::....||:::.:|..|:..:....
plant   163 FNEVKPALEIHLNSSDKEILRYVCLAISHLCYGSVDGIQRVIQAGFVPKLVSVLRRPSPVLSAPE 227

  Fly   252 LQALINIATGSEEQIQELLNNNLLPHLSALMSNSDPDIRCQVLKLLLNIADGNIFQRHAIMNAGL 316
            |:.:..:.||:..|.|.|::.||:|....|..|::.||:.:.::::|....|.
plant   228 LRTIGTLVTGNNHQSQLLIDANLIPSSVNLALNAELDIKREAVRVILRATVGG------------ 280

  Fly   317 LHKILECLKADAISLKSAAALTITTLAIDKDKNLLCYLMRQGVIPEFCNLLFCQERDILSNVLDI 381
                                          ..|.:.||::||.....|:||.|.:..|:...|..
plant   281 ------------------------------SPNQIKYLVQQGCTKLLCDLLVCPDIMIIKLCLYG 315

  Fly   382 LSTMLDVDPSFS--AEVS---GIIEWSGALNNIRMLQSSEHEEIAAVARKIIGNYF 432
            |..:|....|..  .:|:   .:|:.:..:..|:.|...|..||...|..|:..|:
plant   316 LKNILKAGESEKNRGDVNYYRQLIDAAEGVKKIKNLLKHERNEIYDKALNILETYW 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alphaKap4	NP_648007.1	ARM	57..177	CDD:237987	35/118 (30%)
		armadillo repeat	98..134	CDD:293788	12/35 (34%)
		armadillo repeat	140..176	CDD:293788	11/35 (31%)
		ARM	189..301	CDD:237987	29/112 (26%)
		armadillo repeat	192..217	CDD:293788	6/24 (25%)
		armadillo repeat	224..260	CDD:293788	7/35 (20%)
		armadillo repeat	266..300	CDD:293788	10/33 (30%)
		ARM	276..385	CDD:237987	19/108 (18%)
		armadillo repeat	308..342	CDD:293788	0/33 (0%)
		armadillo repeat	350..383	CDD:293788	10/32 (31%)
		Arm_3	400..>433	CDD:292804	9/33 (27%)
AT5G49305	NP_001331293.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	58	1.000	Domainoid score	I3982
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54553
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000157
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23316
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020