Protein Alignment alphaKap4 and Kap-alpha3

DIOPT Version :10

• Sequence 1: NP_648007.1
• Gene: alphaKap4 / 38675
• FlyBaseID: FBgn0035657
• Length: 442
• Species: Drosophila melanogaster
• Sequence 2: XP_321878.4
• Gene: Kap-alpha3 / 1281905
• VectorBaseID: AGAMI1_013593
• Length: 518
• Species: Anopheles gambiae
• Alignment Length: 477
• Identity: 165/477 - (34%)
• Similarity: 264/477 - (55%)
• Gaps: 49/477 - (10%)

  Fly     2 QKRKRRFLKKGQNLMMLR------TLRLEKAKKAEL---------------QKELTIYNALTKC- 44
            :.|.:.|..||::...:|      |:.|.|.|:.|.               :::.|:.:.|.|.
Mosquito     9 KNRMQGFKNKGKDQDEMRRRRTEVTVELRKNKREETILKRRNVPQTTESTDEEDYTLQSNLKKLV 73

  Fly    45 --------------------KLTSSEVVPDVNKLLKSNTIGNLVESLGHGNKNKIRADAADALAH 89
                                :|.||:..|.:|.|:.|..:..||..|...:...::.:||.||.:
Mosquito    74 EKAGNSSDKEGQLAAVQAARRLLSSDRNPPINNLIDSGILPILVNCLEQDDNQVLQFEAAWALTN 138

  Fly    90 IASGSSEHSNLIAKAGAVPRLIRLLQSPDPEVCEKGILSLGNLLHFAPNLRDYIIRHGLMQKLMS 154
            ||||::..:|.:.:|||||..:|||.||.|.|||:.:.:|||::...|:||||:|:.|::|.|:|
Mosquito   139 IASGTAAQTNQVVRAGAVPLFLRLLNSPAPNVCEQAVWALGNIIGDGPSLRDYVIKLGVVQPLLS 203

  Fly   155 IIQDKSTCTLMLSHVTWVLRKLCISSQPSPPDNAA---EIIQALNIVLYNPEANVLEDALMAVRN 216
            .||.:.... .|.:||||:..||.:..|.||  ||   ||:.|||:::::.:.|:|.|.:.|:..
Mosquito   204 FIQPEIPIP-FLRNVTWVIVNLCRNKDPPPP--AATILEILPALNMLIHHTDINILVDTVWALSY 265

  Fly   217 LAH-GNETIQMLLDFEVVPRIIYLLEHPNVTVQNAALQALINIATGSEEQIQELLNNNLLPHLSA 280
            |.. |||.||:::|..|||::|.||.|..|.||.|||:|:.||.|||::|.|.:||.:.|.|...
Mosquito   266 LTDGGNEQIQLVIDSGVVPKLIPLLSHVEVKVQTAALRAVGNIVTGSDDQTQVVLNCDALSHFPK 330

  Fly   281 LMSNSDPDIRCQVLKLLLNIADGNIFQRHAIMNAGLLHKILECLKADAISLKSAAALTITTLAID 345
            |:::|...||.:.:..|.||..||..|..|:::||||.|::|.||......:..||..|:.|.|.
Mosquito   331 LLTHSKDKIRKEAVWFLSNITAGNQSQVQAVIDAGLLPKVIENLKHGDFHTQKEAAWAISNLTIS 395

  Fly   346 KDKNLLCYLMRQGVIPEFCNLLFCQERDILSNVLDILSTMLDVDPSFSAEVSGIIEWSGALNNIR 410
            .::..:..|:..|.:|.||:||.||:..:::.|||.::.||.:....:..|:.:||....::.|.
Mosquito   396 GNREQVAQLINDGAVPPFCDLLMCQDCQVINVVLDGINNMLKLAGPHAEHVANLIEECDGVSKIE 460

  Fly   411 MLQSSEHEEIAAVARKIIGNYF 432
            :||:.|:.||..:|..||..:|
Mosquito   461 VLQNHENVEIYKLAYDIIEQFF 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaKap4	NP_648007.1	SRP1	45..432	CDD:227396	151/390 (39%)
		armadillo repeat	98..134	CDD:293788	18/35 (51%)
		armadillo repeat	140..176	CDD:293788	15/35 (43%)
		armadillo repeat	192..217	CDD:293788	7/24 (29%)
		armadillo repeat	224..260	CDD:293788	19/35 (54%)
		armadillo repeat	266..300	CDD:293788	10/33 (30%)
		armadillo repeat	308..342	CDD:293788	12/33 (36%)
		armadillo repeat	350..383	CDD:293788	12/32 (38%)
Kap-alpha3	XP_321878.4	SRP1	8..510	CDD:227396	165/477 (35%)
		armadillo repeat	107..139	CDD:293788	9/31 (29%)
		armadillo repeat	147..183	CDD:293788	18/35 (51%)
		armadillo repeat	189..224	CDD:293788	15/35 (43%)
		armadillo repeat	241..266	CDD:293788	7/24 (29%)
		armadillo repeat	274..310	CDD:293788	19/35 (54%)
		armadillo repeat	316..350	CDD:293788	10/33 (30%)
		armadillo repeat	358..392	CDD:293788	12/33 (36%)
		armadillo repeat	401..435	CDD:293788	12/33 (36%)