Protein Alignment alphaKap4 and kpna4

DIOPT Version :10

• Sequence 1: NP_648007.1
• Gene: alphaKap4 / 38675
• FlyBaseID: FBgn0035657
• Length: 442
• Species: Drosophila melanogaster
• Sequence 2: XP_002933281.2
• Gene: kpna4 / 100380091
• XenbaseID: XB-GENE-1011058
• Length: 520
• Species: Xenopus tropicalis
• Alignment Length: 477
• Identity: 161/477 - (33%)
• Similarity: 253/477 - (53%)
• Gaps: 48/477 - (10%)

  Fly     3 KRKRRFLKKGQNLMMLRTLR------LEKAKKAE--LQK-------------------------E 34
            :|.:.|..||::|..:|..|      |.|.|:.|  |::                         |
 Frog    10 QRLKNFKNKGRDLESMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDICEDSDVDADFRVQNTSLE 74

  Fly    35 LTIYNALT------------KCKLTSSEVVPDVNKLLKSNTIGNLVESLGHGNKNKIRADAADAL 87
            ..:.||.:            ..||.||:..|.::.|:||..:..||..|...:...::.:||.||
 Frog    75 AIVQNASSDHQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWAL 139

  Fly    88 AHIASGSSEHSNLIAKAGAVPRLIRLLQSPDPEVCEKGILSLGNLLHFAPNLRDYIIRHGLMQKL 152
            .:||||:||.:..:.::.|||..:|||.||...|||:.:.:|||::...|..|||:|..|:::.|
 Frog   140 TNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPL 204

  Fly   153 MSIIQDKSTCTLMLSHVTWVLRKLCISSQPSPP-DNAAEIIQALNIVLYNPEANVLEDALMAVRN 216
            :|.|......| .|.:||||:..||....|.|| :...||:.||.:::::.:.|:|.|.:.|:..
 Frog   205 LSFINPSIPIT-FLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHTDVNILVDTVWALSY 268

  Fly   217 LAH-GNETIQMLLDFEVVPRIIYLLEHPNVTVQNAALQALINIATGSEEQIQELLNNNLLPHLSA 280
            |.. |||.|||::|..:|..::.||.:|.|.||.|||:|:.||.||::||.|.:||.:.|.|..|
 Frog   269 LTDAGNEQIQMVIDSGIVTNLVPLLSNPEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALLHFPA 333

  Fly   281 LMSNSDPDIRCQVLKLLLNIADGNIFQRHAIMNAGLLHKILECLKADAISLKSAAALTITTLAID 345
            |::::...|..:.:..|.||..||..|..|:::|.|:..|:..|.......:..||..|:.|.|.
 Frog   334 LLTHAKEKINKEAVWFLSNITAGNQQQVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTIS 398

  Fly   346 KDKNLLCYLMRQGVIPEFCNLLFCQERDILSNVLDILSTMLDVDPSFSAEVSGIIEWSGALNNIR 410
            ..|:.:.||::|.|||.|||||..::..::..|||.||.:|.:....|..::.:||..|.|..|.
 Frog   399 GRKDQVAYLIQQNVIPPFCNLLTVKDPQVIQVVLDGLSNILKMADEDSETIANLIEECGGLEKIE 463

  Fly   411 MLQSSEHEEIAAVARKIIGNYF 432
            .|||.|:|:|..:|.:||..:|
 Frog   464 QLQSHENEDIYKLAFEIIDQFF 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
alphaKap4	NP_648007.1	SRP1	45..432	CDD:227396	145/388 (37%)
		armadillo repeat	98..134	CDD:293788	14/35 (40%)
		armadillo repeat	140..176	CDD:293788	14/35 (40%)
		armadillo repeat	192..217	CDD:293788	6/24 (25%)
		armadillo repeat	224..260	CDD:293788	17/35 (49%)
		armadillo repeat	266..300	CDD:293788	9/33 (27%)
		armadillo repeat	308..342	CDD:293788	8/33 (24%)
		armadillo repeat	350..383	CDD:293788	14/32 (44%)
kpna4	XP_002933281.2	SRP1	11..519	CDD:227396	161/476 (34%)
		armadillo repeat	73..98	CDD:293788	3/24 (13%)
		armadillo repeat	109..142	CDD:293788	10/32 (31%)
		armadillo repeat	150..186	CDD:293788	14/35 (40%)
		armadillo repeat	192..227	CDD:293788	14/35 (40%)
		armadillo repeat	244..269	CDD:293788	6/24 (25%)
		armadillo repeat	279..311	CDD:293788	13/31 (42%)
		armadillo repeat	319..355	CDD:293788	11/35 (31%)
		armadillo repeat	361..395	CDD:293788	8/33 (24%)
		armadillo repeat	404..438	CDD:293788	16/33 (48%)