Protein Alignment CG10479 and shc-2

DIOPT Version :10

• Sequence 1: NP_001261458.1
• Gene: CG10479 / 38674
• FlyBaseID: FBgn0035656
• Length: 379
• Species: Drosophila melanogaster
• Sequence 2: NP_494915.2
• Gene: shc-2 / 173860
• WormBaseID: WBGene00020867
• Length: 638
• Species: Caenorhabditis elegans
• Alignment Length: 345
• Identity: 74/345 - (21%)
• Similarity: 129/345 - (37%)
• Gaps: 76/345 - (22%)

  Fly    21 SKKDTQQKNKMLRNAIKCPGYSDIYGQYNKDSSFEKCDEWSNKLQFPAAGEMDKQEPIQSRTHKV 85
            |.|:.::...:||||                          |:.|..|| :..|.....|..|..
 Worm   252 SLKEAEEIENVLRNA--------------------------NQSQVLAA-KQPKSAVSTSSMHPT 289

  Fly    86 YDSMKSFLQRKLFAQPSHKEQILNEEPTSDYDEQDLLDSSYHADAEEEEEERDADCSCSSTGSSS 150
              :..|.:..|..|......:.|.::.:...||          ..:.:.:.|......||.....
 Worm   290 --NTASTMTEKRSASTVFLNRFLGKKGSQTVDE----------SGQCKRKRRPVSAVFSSAIHRL 342

  Fly   151 TSSSSPTTPKR----SPQ----KSLLSLNCWQSSQPSSDSNPEEEQDEEAEEDSDAGISDCCQLL 207
            :||:|...|||    .||    :.||.|   |:....:.|:|..|:....:..:.:..:....:.
 Worm   343 SSSTSSVNPKRMSTIEPQAPTREQLLQL---QNQMRCAASSPVPEEPRPTDLCAASTTTSTSSVA 404

  Fly   208 AENSPNTMSKRRRAAPLFTRYISANQNS---DD---------DEDEEPELLACPWYQPRITAKAA 260
            :.:|.|..|.....:|:    ..|.|.:   |:         |:....:|..|.::..:.|..:.
 Worm   405 SSSSSNGSSSSTDTSPV----PPAPQTALVYDEKLGEWIYPIDQALMTQLDNCSYFVGQPTKDSM 465

  Fly   261 LEHLQQATPGSFLLRRSTPRHFELVLRL-----ERNNKVKTYPVQSTRN-QMYRLK--GAKKQFT 317
            :.:|.....|:|::|.|..:...|.|.:     ...:.:..|.:  .|| |.:|||  ..||.|.
 Worm   466 VYNLNTQPEGAFVIRYSESKSKCLALSMRVPCSHNPSGISHYLI--IRNEQGFRLKLSATKKPFP 528

  Fly   318 SLKALITHHSVMAEQLPLVL 337
            :|:.::|||||:...||..|
 Worm   529 TLQMMLTHHSVLESHLPCTL 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10479	NP_001261458.1	SH2	249..326	CDD:198173	20/84 (24%)
shc-2	NP_494915.2	PH-like	152..268	CDD:473070	6/41 (15%)
		SH2	454..537	CDD:198173	20/84 (24%)