Protein Alignment Rcc1 and SRM1

DIOPT Version :9

• Sequence 1: NP_523943.1
• Gene: Rcc1 / 38669
• FlyBaseID: FBgn0002638
• Length: 547
• Species: Drosophila melanogaster
• Sequence 2: NP_011418.1
• Gene: SRM1 / 852782
• SGDID: S000003065
• Length: 482
• Species: Saccharomyces cerevisiae
• Alignment Length: 518
• Identity: 145/518 - (27%)
• Similarity: 214/518 - (41%)
• Gaps: 106/518 - (20%)

  Fly     1 MPRRKALTNNNNAGEAEQQPPKAKRARIAFHLELPKRRTVLG----NVLVCGNGDVGQLGLG--- 58
            |.:|...||.:.:|....:......|....:.:...:...|.    ::...|.|.:.:||||
Yeast     1 MVKRTVATNGDASGAHRAKKMSKTHASHIINAQEDYKHMYLSVQPLDIFCWGTGSMCELGLGPLA 65

  Fly    59 -EDILERKRLSPVAGIPDA--VDISAGGMHNLVLTKSGDIYSFGCNDEGALGRDTS--------- 111
             ...::|.||:|.....:|  :..:.||||.|.|.:..:::|:||||.||||||||
Yeast    66 KNKEVKRPRLNPFLPRDEAKIISFAVGGMHTLALDEESNVWSWGCNDVGALGRDTSNAKEQLKDM 130

  Fly   112 --------EDGS-------------ESKPDLIDLPGKALCISAGDSHSACLLEDGRVFAWGSFRD 155
                    |||.             ||.|.|.: ..|.:.::|.|:.|..|..:|.|:|||:||.
Yeast   131 DADDSSDDEDGDLNELESTPAKIPRESFPPLAE-GHKVVQLAATDNMSCALFSNGEVYAWGTFRC 194

  Fly   156 SHGNMGLTIDGNK--RTP--IDLMEGTVCCSIASGADHLVILTTAGKVFTVGCAEQGQLGR-LSE 215
            :.|.:|...|..|  :||  :..........:|.|.||::.|...|.||..|..:|.|||| :.|
Yeast   195 NEGILGFYQDKIKIQKTPWKVPTFSKYNIVQLAPGKDHILFLDEEGMVFAWGNGQQNQLGRKVME 259

  Fly   216 RSISGEGRRGKRDLLRPTQLIITRAKPFEAIWATNYCTFMRESQTQVIWATGLNNFKQ--LAHET 278
            |.        :...|.|....:...|...:  ..|:|..:.:....|.|  |||.|.|  ::.:.
Yeast   260 RF--------RLKTLDPRPFGLRHVKYIAS--GENHCFALTKDNKLVSW--GLNQFGQCGVSEDV 312

  Fly   279 KGKEFALTPIKTELKD---IRHIAGGQHHTVILTTDLKCSVVGR-------------PEYGRLGL 327
            :.......|.:..|.|   ||.||.|:||::||:.|......||             |||
Yeast   313 EDGALVTKPKRLALPDNVVIRSIAAGEHHSLILSQDGDLYSCGRLDMFEVGIPKDNLPEY----- 372

  Fly   328 GDVKDVVEKPTIVKKLTE-----KIVSVGCGEVCSYAVTIDGKLYSWGSGVNNQLGVGDGDDELE 387
             ..|||..|...|...|:     |..||..|...|.||..:|..||||.|....:|:|..:|:.|
Yeast   373 -TYKDVHGKARAVPLPTKLNNVPKFKSVAAGSHHSVAVAQNGIAYSWGFGETYAVGLGPFEDDTE 436

  Fly   388 -PIVVVSKNTQGKHMLLASGGGQHAIFLVKADKQDQKENVPVKVSGSSSISKKDKTPPQDNVD 449
             |..:.:..||..:::|...|||.:                  |||...:|.:|.....|.:|
Yeast   437 VPTRIKNTATQDHNIILVGCGGQFS------------------VSGGVKLSDEDAEKRADEMD 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	16/56 (29%)
		RCC1	92..141	CDD:278826	24/78 (31%)
		RCC1_2	131..158	CDD:290274	11/26 (42%)
		RCC1	144..193	CDD:278826	17/52 (33%)
		RCC1_2	182..209	CDD:290274	10/26 (38%)
		RCC1	363..414	CDD:278826	17/51 (33%)
SRM1	NP_011418.1	ATS1	15..477	CDD:227511	138/498 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342085
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55567
Inparanoid	1	1.050	140	1.000	Inparanoid score	I1183
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58672
OrthoFinder	1	1.000	-	-		FOG0004765
OrthoInspector	1	1.000	-	-		oto99824
orthoMCL	1	0.900	-	-		OOG6_100545
Panther	1	1.100	-	-	LDO	PTHR45982
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1072
SonicParanoid	1	1.000	-	-		X2826
TreeFam	1	0.960	-	-
	14	13.790