DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rcc1 and ATS1

DIOPT Version :9

Sequence 1:	NP_523943.1	Gene:	Rcc1 / 38669	FlyBaseID:	FBgn0002638	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_009382.2	Gene:	ATS1 / 851213	SGDID:	S000000018	Length:	333	Species:	Saccharomyces cerevisiae

Alignment Length:	344	Identity:	72/344 - (20%)
Similarity:	121/344 - (35%)	Gaps:	107/344 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 VLVCGNGDVGQLGLG--EDILERKRLSPVAGIPDAV--DISAGGMHNLVLTKSGDIYSFGCNDEG 104
            |...|:....|||||  ||:...:|..|  |...|:  .|:.||.|:::||..|::...|.|..|
Yeast     4 VYAFGSNGQRQLGLGHDEDMDTPQRSVP--GDDGAIVRKIACGGNHSVMLTNDGNLVGCGDNRRG 66

  Fly   105 ALGRDTSEDGSES-------KPDLIDLPGKALCISAGDSHSACLLEDGRVFAWG----SFRDSHG 158
            .|      |.:::       :|  :::|...:.::.|...:..:..||||:..|    .|...|.
Yeast    67 EL------DSAQALRQVHDWRP--VEVPAPVVDVACGWDTTVIVDADGRVWQRGGGCYEFTQQHV 123

  Fly   159 NMG---------------LTIDGNK------RTPIDLME---------------GTVCCS-IASG 186
            .:.               :.:.|.:      .|...|.|               |:|... :|.|
Yeast   124 PLNSNDERIAVYGCFQNFVVVQGTRVYGWGSNTKCQLQEPKSRSLKEPVLVYDTGSVAVDYVAMG 188

  Fly   187 ADHLVILTTAGKVFTVGCAEQGQLGRLSERSISGEGRRGKRDLLRPTQLIITRAKPFEAIWATNY 251
            .|.:||:...|::....       |||.      .|...|:...|...:::       .:|.:.:
Yeast   189 KDFMVIVDEGGRIVHAS-------GRLP------TGFELKQQQKRHNLVVL-------CMWTSIH 233

  Fly   252 CTFMRESQTQVIWATGLNNFKQLAHETKGKEFALTPIKTELKD--IRHIAGGQHHTVILTTDLK- 313
                       :|...||..:.....|..:.|     ..|..|  |..:|.|..|.::.|.:.:
Yeast   234 -----------LWNARLNTVESFGRGTHSQLF-----PQERLDFPIVGVATGSEHGILTTANQEG 282

  Fly   314 ---CSVV---GRPEYGRLG 326
               |..|   |..|:|..|
Yeast   283 KSHCYNVYCWGWGEHGNCG 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rcc1	NP_523943.1	RCC1	42..89	CDD:278826	17/48 (35%)
		RCC1	92..141	CDD:278826	9/55 (16%)
		RCC1_2	131..158	CDD:290274	7/30 (23%)
		RCC1	144..193	CDD:278826	17/89 (19%)
		RCC1_2	182..209	CDD:290274	6/27 (22%)
		RCC1	363..414	CDD:278826
ATS1	NP_009382.2	ATS1	1..333	CDD:227511	72/344 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5184
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900